
Intro
I am excited to announce one of the most potent fat loss and endurance drugs available in today’s fitness community which is called Cardarine (GW501516). Although it is sometimes referred to, or sold as, a SARM (selective androgen receptor modulator), it is actually nothing of the sort. In actuality, it is a PPAR (Peroxisome proliferator-activated receptor beta) receptor agonist. In this article, I’m going to tell you why it is a mistake not to include this amazing performance drug in your stack.

Medical History
Many people have only recently heard from a friend about Cardarine (GW-501516), and it is usually referred to as this weird pill or liquid they take that helps them during a road race, the gym, or at CrossFit. Naturally, they assume it is brand new, however they would be very wrong.
Cardarine (GW501516) was developed all the way back during Bill Clinton’s early years as president in the early 1990’s. This was before the internet was in most peoples homes, before the first CrossFit gym opened, and before we even had planet fitness. At that time it was the pharmaceutical companies GlaxoSmithKline (GSK) and Ligand which wanted something to help with tumor growth. Phase 1 trials were done several years later and there was the potential to treat poor heart health. Then they found out how effective it was with obesity and diabetes. By 2008, Cardarine (GW 501516) had been medically abandoned and it is not known to as why.
Discovery in athletics
It is unclear who or how Cardarine (GW501516) was leaked into the fitness community. We know that during the 2008 China Olympics a huge percentage of competitors were using it, and by 2009 the WADA (the Olympic doping agency) had banned its use. Once the actual ban took place is when research companies saw an opportunity, and some very savvy entrepreneurs started importing raws from China to produce it to sell. From there Cardarine (GW 501516)’s use spread like wildfire, and today walk into any CrossFit gym or talk to your endurance buddies and they will know about it. It was also routinely sold legally on eBay, Amazon, and other large websites for several years before those sites started cracking down on sales.
How it works
The science behind how Cardarine (GW-501516) is actually quite simple. Since it is a PPAR (Peroxisome proliferator-activated receptor beta) agonist it binds to the receptors. The gene activity is altered, which causes a change in energy output. This type of thing will cause a sharp boost in endurance in the body, allowing you to go harder and longer, without getting winded as easily.
From a ‘bro’ outlook your heart rate will not get as revved up while on this compound. Just imagine your heart was the RPM’s on a car and you were pushing hard on the gas, well if you slam too hard the RPM’s will go into the red zone causing your engine to burn up. If you added Cardarine (GW501516) to your car your RPM’s would not go into the red, so you can ‘rev up’ your body the same way.
Health benefits
Let’s also reveal the other things Cardarine (GW 501516) can do for you.
Heart health:

Studies have shown it will cause a drop in bad cholesterol LDL, and increase good cholesterol HDL.
GW501516 produced significant changes in HDL cholesterol, LDL cholesterol, apoA1, and apoB. Fewer very LDL and larger LDL support a transition toward less atherogenic lipoprotein profiles. These data are consistent with peroxisome proliferator-activated receptor-δ being a potentially important target for providing cardiovascular protection in metabolic syndrome-like patients. (1)
Diabetes:
If you are at risk of type 2 diabetes there is a chance that using Cardarine (GW501516), combined with an improved diet, can reverse it before it is too late.

Fat loss
One of the great things about Cardarine (GW 501516) is that even those who are fat can use it safely. Obviously, if you are in good shape already, you can lose more fat on it too. The way it helps with fat loss is it can change the way our body treats nutrients by increasing glucose uptake. The end result is a huge reduction in fat being stored.
In fact, many users have even said they didn’t even workout or change their diets. And they used Cardarine (GW501516) and still lost fat. I must reveal that in studies those who did improve diet and exercised more had even better results, so the more you try the more results you will get. It creates a very positive domino effect and will enhance fat loss to make things easier for you.
Side effects
Cardarine (GW-501516) has no side effects that we can see so far. It is completely nonhormonal, so there is no suppression to worry about. Studies have been done on humans that have taken it for up to 6 months with zero adverse issues.
How To Use Cardarine
During cycle
Cardarine (GW501516) is a popular choice to use in an anabolic steroid cycle because it will help with heart issues, endurance, and fat loss.
It is especially a good idea to use it with your harshest steroids, such as Trenbolone. Because of its ability to counteract the negative side effects of these strong androgenic compounds. Normal dosages range from 10-20mgs per day.
SARM’s (selective androgen receptor modulator’s) are also popularly stacked with Cardarine (GW 501516) for the same reasons mentioned above. If you want to increase endurance, you can stack it at 20mgs per day with a SARM such as LGD-4033 (anabolicum or ligandrol) at 10mgs per day.
If you want to boost fat loss, stack it at 20mgs per day with S4 (andarine) at 50mgs per day.
During post cycle
Cardarine (GW-501516) works beautifully during your post cycle therapy since it is nonhormonal and will counteract the bodies desire to put on body fat during stress. It also will help you push harder during your workouts.
Stand-alone
Anybody can use Cardarine (GW501516) as a stand-alone by itself. Just use it at 10-20mgs per day.
Half-life and detection time
The half-life is thought to be about 24 hours. This means you can dose the product 1-2X per day with good results. The detection times are unknown. But users have said they have passed doping tests when stopping the drug 1 month prior.
Where to buy
Cardarine (GW 501516) is getting harder to find as the government and credit card financial institutions begin cracking down. Also, many research sites have been known to lace their products with either clenbuterol or prohormones, unknowingly to their customers. This is not only unethical but it is dangerous. The key is to always buy your Cardarine (GW-501516) from an approved source. Please see our forums at evolutionary.org and elitefitness.com to find legitimate places to buy.

References:
- Lipid effects of peroxisome proliferator-activated receptor-δ agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome.
Olson EJ1, Pearce GL, Jones NP, Sprecher DL. - A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice.
Chen W1, Gao R2, Xie X1, Zheng Z1, Li H2, Li S1, Dong F2, Wang L1.
Cardarine Review
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Boost Endurance
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Burn Fat
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Protect Heart