institute for cancer research

A.P.John

CAAT Protocol for Physicians

CANCER TREATMENTS ARE DIFFERENT

In the chart below you will note that most chemotherapeutic drugs and radiation work by either poisoning or interfering with DNA synthesis. All of these drugs cause some degree of toxic effects and many have been shown to produce cancer in laboratory animals.

CAAT on the other hand, attacks cancer on several fronts and has minimal side effects.

Chemotherapy
Drugs & Integrative
Therapy
Type of Cancers Treated Interferes with/ or 
Poisons DNA
Prevents
Angioge
nesis
Attacks
Glycolysis
Inhibits Production
of Tumor
Growth
Factors
Disrupts Mitosis
or Cell Divisions
Toxic Effects
5-Fluorouracil Colon & Others X - - - - Yes
Cisplatin Brain & Others X - - X - Yes
Cyclophosphamide Many X - - X - Yes
Carboplatin Many X - - X - Yes
Methotrexate Leukemia & Others X - - - - Yes
Adriamycin Breast & Others X - - X - Yes
Tamoxifen Breast & Others - - - X - Yes
Etoposide Many X - - - - Yes
Mitomycin C Many X - - - - Yes
Vinblastine Lung & 
Others
X - - - - Yes
Topetecan Ovarian & Lung X - - - - Yes
Radiation All Cancers X - - - X Yes
CAAT All Cancers X X X X X Minimal

CHARTS

Glycolysis - Metabolism of Carbohydrate Chart

GLYCOLYSIS: The above illustration depicts the eleven enzymatic reactions in which glucose is broken down into a smaller molecule called pyruvic acid. During this process energy is produced. Normal cells derive approximately 20 to 30 percent of their total energy through this process called Glycolysis. Cancer cells, on the other hand, depend almost entirely upon Glycolysis for most of their daily energy needs. The reason being that cancer cells have a defective mitochondria, the compartment in all cells that house the Krebs or citric acid cycle. It is the Krebs cycle that provides the cells of the body with their major supply of energy. (Source: Review of Physiological Chemistry)

 

KREBS Cycle - The Citric Acid Cycle

KREBS OR CITRIC ACID CYCLE: In normal cells, after glucose is broken down to pyruvic acid it is then carried into the mitochondria and totally combusted by some twelve enzymatic reactions into carbon dioxide and water. From the breakdown of pyruvic acid and fats through the Krebs cycle, normal cells derive approximately 70 percent of their total energy needs. However, because cancer cells have a defective Krebs cycle, they must derive almost all of their energy needs from Glycolysis. CAAT is designed to cripple the enzymes that function in Glycolysis thereby literally starving cancer cells to death. Normal cells are not affected because they have an intact Krebs cycle to provide them with their daily energy needs. (Source: Review of Physiological Chemistry)

Physician information National Cancer Institute Reprint & Research Studies Chart: Cancer Treatments are Different
Glycolysis and Krebs Cycle Charts
 

© 2003 - Cancer Treatment - Prevention - Research - A.P.John Cancer Institute
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