institute for cancer research

What is Thyroid Cancer?

Thyroid cancer is a group of malignant tumors that originate from the thyroid gland. The thyroid is a gland in the front of the neck. The thyroid gland absorbs iodine from the bloodstream so it can produce thyroid hormone (it regulates body metabolism and temperature, it affects the heart rate, and its lack is associated with decrease in energy levels or fatigue). The thyroid gland contains two types of cells: follicular cells, which are responsible for the production of thyroid hormone; and C cells, which make calcitonin, a hormone that participates in the calcium metabolism.

A healthy thyroid gland is barely palpable. A normal gland has two lobes on each side of the windpipe, joined by a narrow strip of tissue called the isthmus. If a mass develops in the thyroid, it is felt as a lump in the neck. A diffusely swollen thyroid gland is called a goiter, which may be due to iodine deficiency. The gland is located on the trachea (windpipe) just below the larynx (voice box) Thyroid tissue growths are known as nodules. Ninety percent (90%) of all thyroid growths are benign and ten percent (10%) of thyroid nodules are malignant. Cancer cells can spread into neighboring tissues and organs, and enter the lymphatic system and the bloodstream.

Here are four types of thyroid cancer:

Papillary Thyroid Cancer - Papillary cancer develops in the follicular cells and grows slowly. It is usually found in one lobe; only 10% to 20% of papillary cancers appear in both lobes.

Follicular Thyroid Cancer - Follicular cancer also develops in the follicular cells and grows slowly, yet is less common. When detected early, it can be treated successfully.

Papillary and follicular cancers make up 80% to 90% of thyroid cancers, and are grouped under the term differentiated thyroid cancer. When detected early, especially in people below the age of 45-50 years, it can be treated successfully.

Medullary Thyroid Cancer - Medullary cancer develops in the C cells. It can be controlled if it is found and treated before it spreads to other parts of the body. Medullary cancer accounts for 5% to 10% of thyroid cancers.

Anaplastic Thyroid Cancer - This is a very rare and aggressive form of thyroid cancer that takes its origin from differentiated thyroid cancer or other benign tumors of the gland, and in its giant cell variety is often rapidly fatal.

As we well know, there are many kinds of cancer; unfortunately they all come about because of the out-of-control growth of abnormal cells.

Healthy Cells vs. Cancer Cells

Healthy cells are like a cat.  They need structure to determine the size of bones and shape of the body, tail and whiskers. The DNA in genes and chromosomes determine this. They need energy to play and prowl and sustain life. This is derived from chemicals in food. Cats need a system to deliver chemicals (food nutrients like amino acids, carbohydrates, fats, vitamins and minerals) to all parts of their body. These are the blood vessels. Growth factors take a kitten into a lazy old cat, all the while helping it to function normally.

The body and its cells are mostly made up of protein. The building blocks of proteins are substances called amino acids that in the form of enzymes and hormones literally control every chemical reaction within the cells. When these are modified, different messages are sent to a complex control system that can alter their function. There are twenty different kinds of amino acids that are essential to life. Twelve of these can be synthesized within the body however; eight must be supplied by the daily diet.

 

 

What causes thyroid cancer?

Doctors do not know what causes most cases of thyroid cancer. However, scientists have observed that thyroid cancer affects women two to three times as often as men and occurs more frequently in whites than in blacks. Scientists do not fully understand the reasons for these patterns; they continue to study thyroid cancer to try to learn what may increase a person's risk for this disease.

One known risk factor is exposure to radiation during childhood. Before doctors knew of its dangers, radiation therapy was used to treat acne and to reduce swelling and infection in organs such as the thymus, tonsils, and lymph nodes. People who received radiation to the head and neck as children have a higher- than-average risk of developing thyroid cancer many years late. Scientists are doing studies to determine whether other types of radiation exposure also can cause thyroid cancer.

Can thyroid cancer be detected early?

The National Cancer Institute recommends that anyone who received radiation to the head or neck in childhood be examined by a doctor every 1 to 2 years. Also, people should see a doctor if they have a family member with medullary thyroid cancer. The most important part of a checkup is the careful examination of the neck, feeling for lumps in the thyroid and enlargement of nearby lymph nodes. A thyroid scan (scintogram) or ultrasonography may be recommended for people at risk for thyroid cancer.

What are symptoms of thyroid cancer?

The most common symptom of thyroid cancer is a lump, or nodule, that can be felt in the neck. Other symptoms are rare. Pain is seldom an early warning sign of thyroid cancer. However, a few patients have a tight or full feeling in the neck, difficulty breathing or swallowing, hoarseness, or swollen lymph nodes. These symptoms can be caused by thyroid cancer or by other, less serious problems. If a person is experiencing symptoms, a doctor should be consulted.

How is thyroid cancer diagnosed?

The doctor can use several tests to learn the size and location of a thyroid nodule and/or to help determine whether a lump is benign (not cancerous) or malignant (cancerous. For example, the doctor may order blood tests to check how well the patient's thyroid is functioning. Also, a radioactive iodine scan can outline abnormal areas of the thyroid. For the scan, the patient is given a very small amount of a radioactive substance (usually iodine I-131 or technetium TC-99m), which collects in the thyroid. An instrument called a scanner can detect "cold spots" (areas in the thyroid that do not absorb iodine normally. Because cold spots can be benign or malignant, further tests are necessary.

Ultrasonography is another technique for producing a picture of the thyroid. In this procedure, high-frequency sound waves, which cannot be heard by humans, pass into the thyroid. The patterns of echoes produced by these waves are converted into a picture (sonogram) by a computer. Doctors can tell whether nodules are fluid-filled cysts, which are usually benign, or solid lumps that might be malignant.

The only sure way to tell whether a patient has thyroid cancer is to look at cells from the thyroid with a microscope. There are two ways to obtain a sample of thyroid tissue: by withdrawing cells using a needle (needle biopsy) or by surgically removing the tumor (surgical biopsy). In either case, a pathologist examines the tissue under a microscope to look for cancer cells.

If the needle biopsy does not show cancer, the doctor may give the patient thyroid hormones. These hormones make it unnecessary for the thyroid to produce its own hormones, and the gland, including the nodule, shrinks and becomes inactive. If the needle biopsy is not conclusive or if the thyroid hormones are not effective, the patient usually has a surgical biopsy.

When thyroid cancer is diagnosed, doctors may do more tests to learn about the stage (extent) of the disease. The results of these tests help doctors plan appropriate treatment.

What treatment is there for thyroid cancer?

Surgery is the most common form of treatment for thyroid cancer that has not spread to distant parts of the body. The surgeon usually removes part or all of the thyroid and any other affected tissue, such as lymph nodes. (If the patient has a surgical biopsy, the biopsy and the removal of the thyroid may be done in the same operation).

Patients with localized papillary or follicular thyroid cancer also may receive treatment with I-131 (a larger dose than that used in a thyroid scan). The patient swallows the iodine, which collects in any thyroid cancer cells that remain in the body after surgery. By damaging such cancer cells, the radioactive iodine helps prevent the disease from recurring. The patient must remain in the hospital for a few days while the radiation is most active. The treatment may be repeated at a later time.

Hormones usually are given to patients who have had surgery to remove the thyroid and/or treatment with radioactive iodine. The hormones replace those that are normally produced by the thyroid. This treatment also slows down the growth of any remaining thyroid cancer cells. The doctor may need to do follow-up tests to determine whether the patient is receiving the proper amount of the necessary hormones.

Surgery may not be recommended when a patient is found to have thyroid cancer that has spread. Treatment usually includes some form of systemic therapy (treatment that can kill or slow the growth of thyroid cancer cells throughout the body), such as chemotherapy, radioactive iodine therapy, and/or hormone therapy.
Regular follow-up is very important after treatment for thyroid cancer. Follow-up care may include periodic complete physician exams, x-rays, scans, and blood tests.

Stages of thyroid cancer

Once thyroid cancer is found (diagnosed), more tests will be done to find out if cancer cells have spread to other parts of the body. This is called staging. A doctor needs to know the stage of the disease to plan treatment.

Papillary and follicular thyroid cancer

The following stages are used for papillary and follicular thyroid cancer:

Stage I

• In patients younger than 45 years, cancer may have spread within the neck or upper chest and/or to nearby lymph nodes but not to other parts of the body.


• In patients aged 45 years and older, the tumor is 2 centimeters (about ¾ inch) or smaller and in the thyroid only.

Stage II

• In patients younger than 45 years, the cancer has spread to distant parts of the body, such as the lung or bone, and may have spread to nearby lymph nodes.


• In patients aged 45 years and older, the tumor is larger than 2 centimeters but not larger than 4 centimeters (between ¾ and 1½ inches) in the thyroid only.

Stage III

The cancer is found in patients aged 45 years or older. The tumor either:

• is larger than 4 centimeters; or


• may be any size and has spread just outside the thyroid and/or to lymph nodes in the neck.

Stage IVA

The cancer is found in patients aged 45 years or older. The tumor may be any size and has spread within the neck and/or to lymph nodes in the neck or upper chest.

Stage IVB

The cancer is found in patients aged 45 years or older. The tumor may be any size and has spread to neck tissues near the backbone or around blood vessels in the neck or upper chest. Cancer may have spread to lymph nodes.

Stage IVC

The cancer has spread to other parts of the body, such as the lung or bone, and may have spread to nearby lymph nodes.

Medullary thyroid cancer

The following stages are used for medullary thyroid cancer:

Stage 0

No tumor is found in the thyroid but the cancer is detected by screening tests. Stage 0 is also called carcinoma in situ.

Stage I

The tumor is 2 centimeters or smaller and in the thyroid only.

Stage II

The tumor is larger than 2 centimeters but not larger than 4 centimeters and is in the thyroid only.

Stage III

The tumor either:

• is larger than 4 centimeters; or


• may be any size and has spread just outside the thyroid and/or to lymph nodes in the neck.

Stage IVA

The tumor may be any size and has spread within the neck and/or to lymph nodes in the neck or upper chest.

Stage IVB

The tumor may be any size and has spread to neck tissues near the backbone or around blood vessels in the neck or upper chest. Cancer may have spread to lymph nodes.

Stage IVC

Cancer has spread to other parts of the body, such as the lung or bone, and may have spread to nearby lymph nodes.

Medullary Thyroid Cancer

Treatment may be one of the following:

1. Total thyroidectomy for tumors in the thyroid only. Lymph nodes in the neck may also be removed.


2. Radiation therapy for tumors that come back in the thyroid as palliative treatment to relieve symptoms and improve the patient's quality of life.


3. Chemotherapy for cancer that has spread to other parts of the body, as palliative treatment to relieve symptoms and improve the patient's quality of life.

Anaplastic thyroid cancer

Anaplastic thyroid cancer is considered to be stage IV thyroid cancer. It grows quickly and has usually spread within the neck when it is found. Anaplastic thyroid cancer develops most often in older people.

Anaplastic Thyroid Cancer

Treatment may be one of the following:

1. Surgery to create an opening in the windpipe, for tumors that block the airway. This is called a tracheostomy.


2. Total thyroidectomy to reduce symptoms if the tumor is in the area of the thyroid only.


3. External-beam radiation therapy.


4. Chemotherapy.


5. Clinical trials of chemotherapy and radiation therapy following thyroidectomy.
6. Clinical trials studying new methods of treatment of thyroid cancer.

Recurrent thyroid cancer

Recurrent disease means that the cancer has come back (recurred) after it has been treated. It may come back in the thyroid or in other parts of the body.

Recurrent Thyroid Cancer

The choice of treatment depends on the type of thyroid cancer the patient has, the kind of treatment the patient had before, and where the cancer comes back. Treatment may be one of the following:

1. Surgery with or without radioactive iodine. A second surgery may be done to remove tumor that remains.


2. Radioactive iodine.


3. External-beam radiation therapy or radiation therapy given during surgery to relieve symptoms caused by the cancer.


4. Chemotherapy.


5. Clinical trials of new treatments.

How thyroid cancer is treated

There are treatments for all patients with thyroid cancer. Four types of treatment are used:

• Surgery (taking out the cancer).


• Radiation therapy (using high-dose x-rays or other high-energy rays to kill cancer cells).


• Hormone therapy (using hormones to stop cancer cells from growing).


• Chemotherapy (using drugs to kill cancer cells).

Surgery is the most common treatment of thyroid cancer. A doctor may remove the cancer using one of the following operations:

• Lobectomy removes only the side of the thyroid where the cancer is found. Lymph nodes in the area may be taken out (biopsied) to see if they contain cancer.


• Near-total thyroidectomy removes all of the thyroid except for a small part.


• Total thyroidectomy removes the entire thyroid.


• Lymph node dissection removes lymph nodes in the neck that contain cancer.

Radiation therapy uses high-energy x-rays to kill cancer cells and shrink tumors. Radiation for thyroid cancer may come from a machine outside the body (external radiation therapy) or from drinking a liquid that contains radioactive iodine. Because the thyroid takes up iodine, the radioactive iodine collects in any thyroid tissue remaining in the body and kills the cancer cells.

Hormone therapy uses hormones to stop cancer cells from growing. In treating thyroid cancer, hormones can be used to stop the body from making other hormones that might make cancer cells grow. Hormones are usually given as pills.

Chemotherapy uses drugs to kill cancer cells. Chemotherapy may be taken by pill, or it may be put into the body by a needle in the vein or muscle. Chemotherapy is called a systemic treatment because the drug enters the bloodstream, travels through the body, and can kill cancer cells outside the thyroid.

Treatment by stage

Treatment of thyroid cancer depends on the type and stage of the disease, and the patient’s age and overall health.

Stage I and II Papillary and Follicular Thyroid Cancer

Treatment may be one of the following:

1. Surgery to remove the thyroid (total thyroidectomy). This may be followed by hormone therapy and radioactive iodine.


2. Surgery to remove one lobe of the thyroid (lobectomy), followed by hormone therapy. Radioactive iodine also may be given following surgery.

Stage III Papillary and Follicular Thyroid Cancer

Treatment may be one of the following:

1. Surgery to remove the entire thyroid (total thyroidectomy) and lymph nodes where cancer has spread.


2. Total thyroidectomy followed by radiation therapy with radioactive iodine or external-beam radiation therapy.

Stage IV Papillary and Follicular Thyroid Cancer

Treatment may be one of the following:

1. Radioactive iodine.


2. External-beam radiation therapy.


3. Surgery to remove the cancer from places where it has spread.


4. Hormone therapy.


5. A clinical trial of new treatments, including chemotherapy.

INTEGRATIVE THERAPY

THE SCIENTIFICALLY FORMULATED AMINO ACID THERAPY

(Keep in mind, CAAT is much more than just a “diet”; it is an amino acid, carbohydrate, & glucose REDUCTION protocol which strategically uses the chemical reactions of amino acids, foods, and nutritional supplements to impair the development of cancer cells, thus starving them to death.) Clinical trials have already been done with humans using amino acid depravation formulas, and with much success. (Journal American Medical Association. 1967; 200:211)

CAAT is a course of therapy to control a patient’s amino acid intake. This is achieved by taking certain foods out of a persons’ daily food plan for a short time and by replacing them with a scientifically supported formula of amino acids. It is also important to emphasize that the food plan that accompanies the amino acid formula needs to be followed so not to offset any of the benefits we are creating by depriving the cancer cells the nutrients they need to grow. Also, it is important to realize that the patient does not need to abandon their conventional cancer treatment, (surgery, chemotherapy, radiation, hormone treatments) nor is it recommended that they do so unless it has already failed them. CAAT works synergistically with chemotherapy and/or radiation to enhance their benefits (see study by Dr. Marco Rabinowitz of the National Cancer Institute). His report on amino acid deprivation, such as with Controlled Amino Acid Therapy (CAAT), proven to inhibit phosphofructokinase which shuts down the energy supply to cancer cells, simultaneously enhancing the benefits of chemotherapy while lessening their toxic side effects. CAAT has also proven to work successfully alone.

Phase 1: CAAT Formulation

The most important component of CAAT is the scientifically formulated amino acids. Based on the specific formula for each cancer, it consists of separate amino acids, citric acid, and small amounts of sodium benzoate. Each formula replaces most of the regular daily proteins found in meats, dairy, fish, beans and nuts, which cancer cells can derive their energy from. The CAAT formula taken two times per day will nourish the healthy cells while causing the cancer cells to starve to death. Of course each individual has specific needs concerning their diet, and this is explained in the second phase of the protocol as well as with a specialist at the Institute when beginning the CAAT therapy.

Phase 2: Daily Food Intake

DISCLAIMER: The following food program SHOULD NOT be consumed without the amino acid formula and without consent from your doctor and our Institute.

Breakfast:
*1/2 Grapefruit or 1-orange or 6-ounces of fresh orange juice.
Whey Enhanced Protein (Vanilla Flavor – Vitamin Shoppe Brand) approximately
10 – 12 grams of protein – read label carefully, based on 150 lb. person ].
A serving of Grits (Butter, cinnamon and other spices are okay).
1 cup of green or black tea (Fructose is sweetener of choice).
* Do Not have ½ grapefruit if taking Chemotherapy

Explanation: ½ Grapefruit or 1 orange or 6 ounces of fresh orange juice are rich in the natural nutrients called Limonene and Citric Acid. Limonene helps shut down the Ras cancer gene which is over active in 90 percent of all cancers. Citric Acid helps shut down glycolosis which in turn helps starve cancer cells to death.

Whey Enhanced Protein (Vanilla Flavor – Vitamin Shoppe Brand) Phosphorus is a nutrient that cancer cells must utilize in order to grow and reproduce. This brand of whey protein is very low in phosphorous and contains no additional vitamins, so when using approximately 10 – 12 grams of protein per 150 lb. person, it helps to protect normal cells, maintain a normal appetite, and also helps to fight edema. (Edema is the swelling or water build up in the legs or other sites in the body)
Whey protein is included in the daily menu of all advanced or metastatic cancer patients. When treating cancers that are stable or have regressed in size, patients then have the option of including other protein foods at their breakfast meals such as cottage cheese, yogurt, or soy foods. Eggs are allowed in the diets of patients with lymphoma and brain cancers.

Grits or Cream of Wheat or 1 slice of white toast or ½ plain bagel or ½ English muffin (Butter is okay)
Grits or white rice is the preferred carbohydrate food at each meal. The other choices are options once the patient’s cancer is stable or reduced in size. Unrefined carbohydrates are included in the CAAT menu instead of whole grains to deprive cancer cells of a certain B-complex vitamin called Pyridoxine (Vitamin B-6). Cancer cells require this vitamin to manufacture certain amino acids that we keep away from through CAAT’s amino acid reduction formula and diet.
Grits is the preferred carbohydrate food at all meals instead of rice, corn, or pasta because it helps deplete Tryptophan in the body, which is essential for the growth and spreading of cancer cells.

1 cup of green or black tea, using fructose as the sweetener of choice. These teas are rich sources of several compounds that help shut down glycolosis and cut off the energy supply to cancer cells. Also, green or regular tea helps to prevent certain hormones and tumor growth factors from stimulating cancer cells to grow and metastasize to other parts of the body. Brassica teas can also be taken because they contain sulphorane, a nutrient that inhibits cancer growth, and also shuts down the cancer genes.
* Why we use fructose as the sweetener of choice will be explained in detail at the end of this phase of the CAAT protocol.

Lunch:

Amino acid formula (4 level plastic scoops) mixed with any of the following: Water & Fructose; Sugar free Kool-Aid; Diet ginger ale; Fresh lemonade & Fructose; Chicken or Beef broth; V8 juice.
Generous amounts of One cooked vegetable or a combination of the following: asparagus, broccoli, cabbage, brussell sprouts, spinach, squash, string beans.
One serving (1/2 cup)of fresh fruit. Choice of: pear, orange, blueberries, raspberries, strawberries.
1 serving (moderate) of grits or corn or rice or pasta (Add tomato sauce or butter)
1 tablespoon of coconut oil
8 to 10 black or green olives
2 tablespoons of vinegar (minimum of 5% acidity) add to vegetables or food
1 cup of green or black tea (Fructose as desired)

Explanation:

This Amino Acid Reduction Formula (4 level plastic scoops may vary) combined with the special diet, allows the CAAT Protocol to reduce certain amino acids in the daily diet of the cancer patient, and is designed to replace most of the animal protein in the diet. Cancer cells require the amino acids glycine, serine, glutamic acid, and aspartic acid to synthesize DNA, build new blood vessels or duplicate its entire contents of proteins. Also, cancer cells require these and certain other amino acids in order to synthesize other proteins that act as growth promoting hormones or tumor growth factors. CAAT impairs the synthesis of a protein called elastin, which is absolutely essential to the manufacture of new blood vessels. The Amino Acid Reduction Formula, diet, certain phytochemicals and herbs work efficaciously to attack cancer cells at each and every biological front.

The generous amounts of one cooked vegetable or a combination of such helps keep normal cells healthy. They are low in carbohydrates and proteins, and high in phytochemicals, compounds which help fight cancer. Patients are allowed to eat these vegetables and salads whenever desired.

The 8 to 10 olives are rich in squalene and oleic acid, nutrients that have been reported to inhibit certain cancer growth factors. The calories in olives also help control body weight and increases ketones in the blood. Ketones help fight cancer by impairing glycolosis – a process in which cancer cells depend almost exclusively upon for their daily supply of energy. Vinegar (and fructose) are two natural products that increase the production of both ACETIC ACID and CITRIC ACID in the body.

Acetic acid and citric acid also help fight cancer by shutting down the process of glycolosis.
Normal cells derive most of their daily energy supply from acetic acid and citric acid, where as cancer cells derive most of their daily energy from glycolosis.

Dinner:

Amino acid formula (4 plastic level scoops) mixed with any of the following: Water & fructose; Sugar free Kool–Ade; Diet Ginger Ale; Fresh lemonade & Fructose; Chicken or Beef broth; V8 Juice.
Generous amounts of One cooked vegetable or a combination of the following: asparagus, broccoli, cabbage, brussel sprouts, spinach, squash, string beans.
One serving (1/2 cup) of stewed plums with fresh cream & fructose; use 4-ounces of orange juice if plums are not in season.
Avacado salad with lettuce, tomatoes, celery, onions, with lemon juice and coconut oil or olive oil.
2 tablespoons of vinegar (minimum of 5% acidity) add to vegetables or food.
1 serving of grits or corn or pasta or rice (Add garlic and butter or tomato sauce)
1 cup of green or black tea (Fructose as desired)

Mid Evening Snack: Ketogenic Cocktail – 2 ounces of fresh cream, ½ ounce each of both coconut & olive oil, 1 tablespoon of Fructose.
Sugar free Jell-O with whipped cream & Fructose or 1 plum or 4 ounces of orange juice.

Explanation: The sugar free jell-o helps to appease the appetite. Plums contain quinlic acid, which is converted into benzoic acid in the body and which in turn helps to deplete the availability of the amino acid Glycine (Glycine is essential to the synthesis of DNA for cancer cells) and the proteins that cancer cells require to build new blood vessels and their tumor growth factors. If underweight take two ounces of light cream and one ounce of olive oil/coconut oil as needed to maintain weight.

Optional Meal:

3 to 4 ounces of Veal, Fish of choice, Beef, Chicken breast, and 1-slice of white bread.

Consume this meal with a minimum of 3 hours before or after taking the amino acids.

Explanation: If the patient is 10 or more pounds underweight or if their albumin levels are below normal is when the optional meal is allowed. This meal should be eaten a minimum of 3 hours before or after taking the amino acids. CAAT provides sufficient protein to maintain the health of normal cells and adequate amounts of calories to maintain desired body weight. Any proteins taken in excess of amounts recommended in the diet will counter act the benefits of the CAAT protocol.

Special Diets: A special diet will be created for any cancer patient whose ability to consume food and liquids has placed them in a critical situation. When a patient is using a feeding apparatus, or they have become too weak or lethargic to eat and drink the daily minimum amount for survival, we will break up the total breakfast, lunch, and dinner over a period of every 2 hours during the entire day until the patient is capable of returning to a daily diet as outlined above.

Carbohydrate and glucose reduction in this diet: CAAT’S dietary menu provides approximately 20 percent of its calories in the form of carbohydrates. Calories need not be a focal point or counted daily. It is recommended that all patients combat their cancers by keeping their body weight at normal or slightly below normal levels. A patient’s desired body weight is regulated by their rate of metabolism, which in turn is regulated by their blood levels of thyroxine, cortisone, insulin, and the amounts of fats and oils in the diet. Studies with human cancer patients and laboratory animals show that reducing the calories of carbohydrates (glucose) in their daily diet by only 10 percent reduced the size of cancerous tumors. When carbohydrate (glucose) calories were reduced 40 percent, the cancers disappeared. It is recommended that those patients who are obese gradually and systematically lose their excess weight to increase the efficiency of the CAAT protocol. Those patients who are underweight shoudn’t gain weight unless they are more than 10 pounds below normal levels. When a patient is underweight due to anorexia or cachexia, such illnesses must be addressed before the CAAT protocol can begin.

Why we use Fructose and Vinegar to treat cancer:

Nobel Prize winner Dr. Otto Warburg discovered more than 50 years ago that all cancer cells produce inordinate amount of lactic acid but he couldn’t explain why.

In 2001 our Institute published the first study to show that cancer cells produce excess amounts of lactic acid because they could not access the oxygen in compartments in the cells called the mitochondria. This provided evidence that cancer cells depend almost exclusively upon glycolosis or the metabolism of glucose as their major source of energy.

Dr. Spitz and Dr. Lee with other cancer researchers published studies showing that when cancer cells are deprived glucose, their energy supply is cut off which causes these cancer cells to commit suicide.

Therefore shutting down glycolosis would be one means of destroying cancer cells because energy can only be derived from glucose through the metabolic process called glycolosis.

Recently our Cancer Institute discovered that both acetic acid and citric acid could inhibit the activity of a key enzyme in glycolosis called phosphofructokinase, which in turn shuts down the process of glycolosis. Our cancer Institute is the first to introduce both fructose and vinegar as treatments for cancer because they either contain or produce acetic acid.

In conclusion, fructose and vinegar are added as supplements to the CAAT protocol because of their acetic acid properties that help shut down glycolosis, shutting off cancer cells energy supply and causing them to die off.

Phase 3: Nutritional Supplements

Nutritional supplements are based on each unique situation. For example, slow-growing cancers produce low levels of toxic free radicals. Tumor cells that grow aggressively produce large amounts of toxic free radicals. The patient will be instructed whether or not to take anti-oxidants (in a nutritional supplement), and at what dosage, according to the levels of toxic free radicals produced in the cancerous cells.

An example of how nutritional supplements can help manipulate cancer cells involves vitamin B-6 (pyroxidine) There are four amino acids essential to the synthesis of DNA. However, those amino acids cannot be synthesized without a certain enzyme, which includes vitamin B-6 among other components. Any supplement containing vitamin B-6 SHOULD NOT be taken during the first 2 months of the CAAT protocol.

The patient will be instructed as to which nutritional supplements or phytochemicals should be purchased and at what dosage strength. Keep in mind that each supplement only complements the CAAT protocol. However, when they are combined they augment the therapeutic benefits of the aminoacid, carbohydrate, and glucose reduction diet.

Parsley: Contains ingredients that can help shut down certain enzymes called Epithelial Growth Factors, which stimulate the growth and spread of cancer. ( CAAT’S amino acid reduction diet works in the same manner )

Vitamin D: Helps activate in many kinds of cancers enzymes called Phosphotases, which literally shut down the activities of other enzymes called Kinases, which are essential to the growth and reproduction of cancer cells.

Green Tea Extract: Phytochemicals in tea help shut down glycolosis (cancer cell’s main supplier of energy) and thereby help to starve cancer cells to death. These effects help complement the effects of CAAT’S carbohydrate reduction.

Anti-Oxidants: The controversy as to whether or not to treat cancer with anti-oxidants is slowly resolving with the current understanding of how they affect the activity of genes and enzymes in cancer cells. The prevailing data shows that the benefits or lack of benefits depend upon the oxidative state the cancer cells are in. Anti-oxidants taken when the cells are in a very high oxidative state may prevent cancer cells from entering apoptosis ( apoptosis is when a cancer cell commits suicide) When oxidative stress in cancer cells is only slightly above normal, anti-oxidants are then expected to stop their growth and reproduction.

Blood Chemistry: Blood tests are usually taken every 6 to 8 weeks, depending upon the results of each test. Not only is it important to monitor the tumor markers but equally important to keep abreast of the overall health of normal tissues and organs. For example, it is important to learn of the health of the kidneys and liver, whether the body is producing sufficient red and white blood cells, etc. Low albumin levels most often indicate insufficient intake of proteins in the diet and this problem would have to be addressed. CAAT is designed to attack cancer but keep the normal cells and tissues functioning harmoniously.

Whey Protein: This protein food is recommended at the breakfast meal to help meet the daily needs of amino acids for the normal cells of the body, and to help keep albumin levels normal and to help prevent edema. We recommend Whey protein purchased from the Vitamin Shoppe because it is the only brand that we have seen with no phosphorous or additional vitamins added to it.

Grits: Grits are also recommended at the breakfast meal in place of whole grains because it is low in vitamin B-6. Cancer cells require B-6 to manufacture the amino acid Glycine, which is required for DNA synthesis. Grits, instead of whole grains, therefore helps prevent cancer cells from manufacturing DNA and building new blood vessels.

Calcium D-Glucurate: This phytochemical helps the body to retain a compound called Glucuronic acid. This is necessary to eliminate both estrogen and testosterone from the body. This is why Calcium D-Glucurate is added to the regiments of patients with breast & prostate cancers. Calcium D-Glucurate is not to be confused with calcium carbonate, which is nothing more than a calcium supplement.

D-Limonene: This phytochemical found mostly in citrus fruits blocks the process called Isoprenylation, which is necessary for tumor growth factors such as the RAS gene, Epithelial Growth factor, Tyrosine Kinase, and Insulin-Like-Growth-factor, to send their signals into the nucleus of a cancer cell and directs them to grow and divide into more cancer cells.

Tocotrienols: This member of the Vitamin E family also helps shut down Isoprenylation and assists D-Limonene in blocking the actions of the various tumor growth factors. More specifically, tocotrienols shut down an enzyme called HMG-2, which is essential to the synthesis of the building blocks that form the Isoprenylation process.

Niacin: This B-Complex vitamin works with D-limonene and the Tocotrienols to shut down the process of Isoprenylation, which as mentioned above prevents the cancer promoting RAS genes from sending signals into the nucleus of the cell. Niacin also helps deplete thee amino acid Glycine, which cancer cells need to synthesize DNA. And by reducing cholesterole in the body, Niacin helps lower the production of estrogen and testosterone.

Choline: This B-complex vitamin is included in our supplement list to help the liver metabolize Niacin and other compounds and to help fight fatigue that accompanies most forms of cancer.

Selenium: Numerous studies show that this mineral can interfere with the activity of certain genes that promote the growth of cancer and to induce cancer cells to commit suicide (apoptosis)

Perilla Oil: This oil is rich in Alpha Linolenic Acid which can inhibit the growth of cancer cells in several ways. One way is to inhibit the synthesis in the body of a tumor growth promotin hormone called Prostaglandin-2, also, Alpha Linolenic Acid inhibits the actions of certain genes that promote the growth of cancer cells. Linolenic acid is not to be confused with linoleic acid, which is a bad fat that stimulates the growth of cancer cells. This bad fat, linoleic acid, is found in all vegetable oils and nuts (With the exception of coconut oil). Olive oil has the least amount of this bad fat.

Super Miraforte: This herb impairs the synthesis of estrogen from testosterone in the body and is included in the regiments of women with breast cancer.
Licorice Root Extract & Pantothenic Acid: This herb and vitamin are added to the regiment when it is desirable to produce steroid like actions in the body. Also used to help patient’s gain weight and to inhibit the growth of lymphomas and leukemia’s.

Resveratrol: This phytochemical blocks the actions of a number of a number of cancer promoting genes thereby causing cancer cells to enter into apoptosis (cell death) and is included in the treatment of all cancers.

Indole-3 Carbinol & D.I.M.: These two phytochemicals block the actions of both estrogen and testosterone and are included in the regiments of both breast and prostate gland cancer.

Melatonin: Numerous studies show that this hormone blocks the synthesis of the cancer promoting chemicals in the body called Leukotrienes, and is included in the treatment of all cancers.

Artho Pro System: This combination of herbs and phytochemicals inhibits the synthesis of the cancer promoting hormone called Prostaglandin-2 and the Leukotriens and replaces the drug celebrex when liver problems are present. The Prostaglandin hormone is over active in most cancers and stimulates cancer growth. The body manufactures the Prostaglandin hormone from the bad fat, Linoleic acid, mentioned above.

Licorice Root Extract & Pantothenic Acid: This HERB and VITAMIN are added to the regiment when it is desirable to produce steroid like actions in the body. Used also to help patients gain weight and ti inhibit the growth of Lymphomas and Leukemias.

CAAT is designed to attack cancer, while keeping normal cells and tissues functioning harmoniously.

* When considering any type of complementary cancer treatment or alternative cancer treatment, always consult with your physician first, as possible interactions could reduce your regimen’s efficacy.

If this information has generated any questions you would like answered.