Hodgkins Disease
What is Hodgkins Disease?
Hodgkins disease is a type of lymphoma, a cancer of the lymph system. When lymphatic cells mutate (change) and grow unregulated by the processes that normally decide cell growth and death, they can form tumors.
The lymph system is made up of thin tubes that branch out to all parts of the body. Its job is to fight infection and disease. The lymph system carries lymph, a colorless fluid containing white blood cells (called lymphocytes).
Groups of bean-shaped organs called lymph nodes are located throughout the body at different sites in the lymph system. There are clusters of lymph nodes in the abdomen, pelvis, underarms, and neck. Other parts of the lymph system are the spleen, which makes lymphocytes and filters blood; the thymus, an organ under the breastbone; and the tonsils, located in the throat.
Hodgkins disease most commonly affects lymph nodes, usually beginning in the neck or the area between the lungs, and behind the breastbone. It can also begin in other groups of lymph nodes, such as those under the arms, in the groin, or in the abdomen or pelvis. If Hodgkins disease spreads, spread to the spleen and liver is fairly common. Spread to other parts of the body can also occur, but is unusual.
Adult Hodgkin's lymphoma is a disease in which malignant (cancer) cells
form in the lymph system.
Adult Hodgkin's lymphoma is a type of cancer that develops in
the lymph system, part of the body's immune system.
The lymph system is made up of the following:
- Lymph: Colorless, watery fluid that travels through the lymph system and carries white blood cells called lymphocytes. Lymphocytes protect the body against infections and the growth of tumors.
- Lymph vessels: A network of thin tubes that collect lymph from different parts of the body and return it to the bloodstream.
- Lymph nodes: Small, bean-shaped structures that filter substances in lymph and help fight infection and disease. Lymph nodes are located along the network of lymph vessels found throughout the body. Clusters of lymph nodes are found in the underarm, pelvis, neck, abdomen, and groin.
- Spleen: An organ that produces lymphocytes, filters the blood, stores blood cells, and destroys old blood cells. It is located on the left side of the abdomen near the stomach.
- Thymus: An organ in which lymphocytes grow and multiply. The thymus is in the chest behind the breastbone.
- Tonsils: Two small masses of lymph tissue at the back of the throat. The tonsils produce lymphocytes.
- Bone marrow: The soft, spongy tissue in the center of large bones. Bone marrow produces white blood cells, red blood cells, and platelets.
- Lymphomas are divided into 2 general types: Hodgkin's lymphoma and non-Hodgkin's lymphoma. (Hodgkin's lymphoma can occur in both adults and children; however, treatment for adults may be different than treatment for children. Hodgkin's lymphoma may also occur in patients who have acquired immunodeficiency syndrome (AIDS); these patients require special treatment.
- Nodular sclerosing Hodgkin's lymphoma.
- Mixed cellularity Hodgkin's lymphoma.
- Lymphocyte depletion Hodgkin's lymphoma.
- Lymphocyte-rich classical Hodgkin's lymphoma.
- Nodular lymphocyte-predominant Hodgkin's lymphoma.
Risk factors for adult Hodgkin's lymphoma include the following:
- Being in young or late adulthood.
- Being male.
- Being infected with the Epstein-Barr virus.
- Having a first-degree relative (parent, brother, or sister) with Hodgkin's lymphoma.
These and other symptoms may be caused by adult Hodgkin's lymphoma or by other conditions. A doctor should be consulted if any of the following problems do not go away.
- Painless, swollen lymph nodes in the neck, underarm, or groin.
- Fevers (unexplained).
- Drenching night sweats.
- Weight loss (unexplained).
- Itchy skin.
- Tiredness.
The following tests and procedures may be used:
- Physical exam and history: An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patient's past illnesses and treatments will also be taken.
- Complete blood count: A procedure in which a sample of blood is drawn and checked for the following:
- The number of red blood cells, white blood cells, and platelets.
- The amount of hemoglobin (the protein that carries oxygen) in the red blood cells.
- The portion of the sample made up of red blood cells.
- Sedimentation rate: A procedure in which a sample of blood is drawn and checked for the rate at which the red blood cells settle to the bottom of the test tube.
- Blood chemistry studies: A procedure in which a blood sample is checked to measure the amounts of certain substances released into the blood by organs and tissues in the body. An unusual (higher or lower than normal) amount of a substance can be a sign of disease in the organ or tissue that produces it.
- Lymph node biopsy: The removal of all or part of a lymph node. A pathologist views the tissue under a microscope to look for cancer cells. One of the following types of biopsies may be done:
- Excisional biopsy: The removal of an entire lymph node.
- Incisional biopsy or core biopsy: The removal of part of a lymph node.
- Needle biopsy or fine-needle aspiration: The removal of a sample of tissue from a lymph node with a needle.
- Immunophenotyping: A test in which the cells in a sample of blood
or bone marrow are looked at under a microscope to find out if malignant
lymphocytes (cancer) began from the B lymphocytes or the
T lymphocytes.
The prognosis (chance of recovery) and treatment options depend on the following:
- The patient's symptoms.
- The stage of the cancer.
- The type of Hodgkin's lymphoma.
- Blood test results.
- The patient's age, gender, and general health.
- Whether the cancer is recurrent or progressive.
As we well know, there are many kinds of cancer; unfortunately they all come about because of the out-of-control growth of abnormal cells.
Healthy Cells vs. Cancer Cells
Healthy cells are like a
cat. They need structure to
determine the size of bones and shape of the body, tail and whiskers. The DNA in
genes and chromosomes determine this. They need energy to play and prowl
and sustain life. This is derived from chemicals in food. Cats need a system to
deliver chemicals (food nutrients like amino acids, carbohydrates, fats,
vitamins and minerals) to all parts of their body. These are the blood
vessels. Growth factors take a kitten into
a lazy old cat, all the while helping it to function
normally.
The body and its cells are
mostly made up of protein. The building blocks of proteins are substances called
amino acids that in the form of enzymes and hormones literally control every
chemical reaction within the cells. When these are modified, different messages
are sent to a complex control system that can alter their function. There are
twenty different kinds of amino acids that are essential to life. Twelve of
these can be synthesized within the body however; eight must be supplied by the
daily diet.
|
Structure |
|
|
Normal
Cells |
Cancer
Cells |
|
DNA in genes and chromosomes go about their business in a normal
way. |
Cancer cells develop a different DNA or gene structure or acquire
abnormal numbers of chromosomes. |
|
Cells divide in an orderly way to produce more cells only when the
body needs them. |
Cells continue to be created without control or order.
If not needed, a mass of tissue is formed which is called a
tumor. |
|
Energy |
|
|
Normal
Cells |
Cancer
Cells |
|
Cells derive 70% of their energy from a system called the “Krebs
Cycle.” |
Cells have a defective “Krebs Cycle” and derive little or no energy
from it. |
|
Cells derive only 20% of their energy from a system called
“Glycolosis.” |
Cancer cells derive almost all their energy from
“Glycolosis.” |
|
Cells derive most of their energy with the use of
oxygen. |
Cells derive most of their energy in the absence of
oxygen. |
|
Blood
Vessels |
|
|
Normal
Cells |
Cancer
Cells |
|
Cells have a built-in blood vessel
system. |
Cells do not have a built-in blood vessel system.
They require more of certain amino acids to
grow. |
|
Growth
Factors |
|
|
Normal
Cells |
Cancer
Cells |
|
While similar to cancer cells, the amount of them is more in
balance to produce a more normal level of
activity. |
These cells have over produced, require more chemicals (food) and
are over active. |
|
Functions |
|
|
Normal
Cells |
Cancer
Cells |
|
The enzymes and hormones go about business in a normal balanced
manner. |
The enzymes and hormones are either over active or under
active. |
|
Tumors are
Different |
|
|
Benign |
Malignant |
|
Benign tumors are not cancerous. They do not invade
nearby tissues nor spread to other parts of the body. They can be
removed and are not a threat to life. |
Malignant tumors are cancerous. They can invade and
damage nearby tissues and organs and they can break away and enter the blood
stream to form new tumors in other parts of the body. The spread of cancer is
called metastasis. |
After adult Hodgkin's lymphoma has been diagnosed, tests are done to find
out if cancer cells have spread within the lymph system or to other parts
of the body.
The process used to find out if cancer has spread within the lymph
system or to other parts of the body is called staging. The information
gathered from the staging process determines the stage of the disease.
It is important to know the stage in order to plan treatment. The following
tests and procedures may be used in the staging process:
- CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography. For adult Hodgkin's lymphoma, CT scans of the chest, abdomen, and pelvis are taken.
- PET scan (positron emission tomography scan): A procedure to find malignant tumor cells in the body. A small amount of radionuclide glucose (sugar) is injected into a vein. The PET scanner rotates around the body and makes a picture of where glucose is being used in the body. Malignant tumor cells show up brighter in the picture because they are more active and take up more glucose than normal cells.
- Bone marrow biopsy: The removal of a small piece of bone and bone marrow by inserting a needle into the hipbone or breastbone. A pathologist views both the bone and bone marrow samples under a microscope to look for signs of cancer.
- Laparotomy: A surgical procedure in which an incision (cut) is made in the wall of the abdomen to check the inside of the abdomen for signs of disease. The size of the incision depends on the reason the laparotomy is being done. Sometimes organs are removed or tissue samples are taken for biopsy. This procedure is done only if it is needed to make decisions about treatment.
- Chest x-ray: An x-ray of the organs and bones inside the chest. An x-ray is a type of energy beam that can go through the body and onto film, making a picture of areas inside the body.
- Needle or surgical biopsy: The removal of tissue using a thin needle or scalpel. A pathologist views the tissue under a microscope to look for cancer cells.
- Thoracentesis: The removal of fluid from the space between the lining of the chest and the lung, using a needle. A pathologist views the fluid under a microscope to look for cancer cells.
Adult Hodgkin's lymphoma may be classified as follows:
- A: The patient has no symptoms.
- B: The patient has symptoms such as fever, weight loss, or night sweats.
- E: "E" stands for extranodal and means the cancer is found in an organ or tissue other than the lymph nodes or extends to tissues beyond, but near, the major lymphatic areas.
- S: "S" stands for spleen and means the cancer is found in the spleen.
Stage I
Stage I is divided into stage I and stage IE.
- Stage I: Cancer is found in a single group of lymph nodes.
- Stage IE: Cancer is found in one area or organ other than the lymph nodes.
Treatment of stage I depends on whether the patient has stage IA (without symptoms) or stage IB (with symptoms) and where the cancer is.
- Stage IA
- Combination chemotherapy with or without radiation therapy.
- Radiation therapy to lymph nodes in the mantle field (neck, chest, and armpits), including those near the aorta, with radiation therapy to the spleen if laparotomy is not done.
- Radiation therapy to the mantle field, with or without laparotomy.
- A clinical trial of combination chemotherapy with or without
radiation therapy.
- Combination chemotherapy and radiation therapy to the mantle field (neck, chest, and armpits).
- A clinical trial of combination chemotherapy with or without
radiation therapy.
- Radiation therapy to the groin.
- Combination chemotherapy with radiation therapy to involved areas.
- A clinical trial of chemotherapy.
- Stage IB. Treatment of stage IB is usually combination chemotherapy with or without radiation therapy.
If the cancer is above the diaphragm and does not involve a large part of the chest, treatment may include the following:
Stage II is divided into stage II and stage IIE.
- Stage II: Cancer is found in two or more lymph node groups on the same side of the diaphragm (the thin muscle below the lungs that helps breathing and separates the chest from the abdomen).
- Stage IIE: Cancer is found in one area or organ other than the lymph nodes and in the lymph nodes near that area or organ, and may have spread to other lymph node groups on the same side of the diaphragm.
Treatment of stage II depends on whether the patient has stage IIA (without symptoms) or stage IIB (with symptoms) and where the cancer is.
- Stage IIA
- Combination chemotherapy with or without radiation therapy.
- Radiation therapy to lymph nodes in the mantle field (neck, chest, and armpits), including those near the aorta, with radiation to the spleen if laparotomy is not done.
- Radiation therapy to the mantle field with or without laparotomy.
- A clinical trial of combination chemotherapy with or without radiation therapy.
- Combination chemotherapy and radiation therapy to the mantle field.
- A clinical trial of combination chemotherapy with or without
radiation therapy.
- Stage IIB. Treatment of stage IIB may include the following:
- Combination chemotherapy with or without radiation therapy.
- A clinical trial of combination chemotherapy with or without radiation therapy.
If the cancer is above the diaphragm and does not involve a large part of the chest, treatment may include the following:
Stage III is divided into stage III, stage IIIE, Stage IIIS, and stage IIIS+E.
- Stage III: Cancer is found in lymph node groups on both sides of the diaphragm.
- Stage IIIE: Cancer is found in lymph node groups on both sides of the diaphragm and in a nearby area or organ other than the lymph nodes.
- Stage IIIS: Cancer is found in lymph node groups on both sides of the diaphragm and in the spleen.
- Stage IIIS+E: Cancer is found in lymph node groups on both sides of the diaphragm, in a nearby area or organ, and in the spleen.
- Stage III(1): Cancer is limited to the upper abdomen above the renal vein.
- Stage III(2): Cancer is found in lymph nodes in the pelvis and/or near the heart.
Treatment of stage III depends on whether the patient has stage IIIA (without symptoms) or stage IIIB (with symptoms) and where the cancer is.
- Stage IIIA
If the cancer does not involve a large part of the chest, treatment may include
the following: - Combination chemotherapy with or without radiation therapy.
- A clinical trial of combination chemotherapy with or without radiation
therapy.
- Combination chemotherapy with radiation therapy.
- A clinical trial of combination chemotherapy with or without radiation therapy.
- A clinical trial of combination chemotherapy and stem cell transplantation.
- Stage IIIB. Treatment of stage IIIB may include the following:
- Combination chemotherapy with or without radiation therapy.
- A clinical trial of combination chemotherapy with or without radiation therapy.
- A clinical trial of combination chemotherapy and stem cell transplantation.
In stage IV, the cancer either:
- is found throughout at least one organ other than the lymph nodes and may be in lymph nodes near those organs; or
- is found in one organ other than the lymph nodes and has spread to lymph nodes far away from that organ.
Treatment of stage IV may include the following:
- Combination chemotherapy.
- A clinical trial of combination chemotherapy with or without radiation therapy.
- A clinical trial of chemotherapy and stem cell transplantation.
- A clinical trial of new treatment options.
Different types of treatment are available for patients with adult Hodgkin's lymphoma. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. Before starting treatment, patients may want to think about taking part in a clinical trial. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment.
Patients with Hodgkin's lymphoma should have their treatment planned by a team of doctors with expertise in treating lymphomas.
Treatment will be overseen by a medical oncologist, a doctor who specializes in treating cancer. The medical oncologist may refer you to other doctors who have experience and expertise in treating adult Hodgkin's lymphoma and who specialize in certain areas of medicine. These may include the following specialists:
- Neurosurgeon.
- Neurologist.
- Rehabilitation specialist.
- Radiation oncologist.
- Endocrinologist.
- Hematologist.
- Other oncology specialists.
Four types of standard treatment are used:
1. Chemotherapy
Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping the cells from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the spinal column, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated. Combination chemotherapy is treatment with more than one anticancer drug.
2. Radiation therapy
Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells. There are two types of radiation therapy. External radiation therapy uses a machine outside the body to send radiation toward the cancer. Internal radiation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer. The way the radiation therapy is given depends on the type and stage of the cancer being treated.
3. Surgery
Laparotomy is a procedure in which an incision (cut) is made in the wall of the abdomen to check the inside of the abdomen for signs of disease. The size of the incision depends on the reason the laparotomy is being done. Sometimes organs are removed or tissue samples are taken for biopsy. If cancer is found, the tissue or organ is removed during the laparotomy.
What are the side effects of treatment for Hodgkin's disease?
The methods used to treat Hodgkin's disease are very powerful. That is why
the treatment often causes side effects - both short-term and permanent. Side
effects depend on the type of treatment and on the part of the body being
treated. Also, each patient may respond differently.
During radiation therapy, patients can become unusually tired as therapy continues.
Resting as much as possible is important. Skin reactions (redness or dryness)
in the area being treated are common. Patients should be gentle with the treated
area of skin. Lotions and creams should not be used without the doctor's advice.
When the chest is treated, patients can have a dry, sore throat and have trouble
swallowing. Sometimes they have shortness of breath or a dry cough. Radiation
treatment to the lower abdomen can cause nausea, vomiting, or diarrhea. Some
patients have tingling or numbness in their arms, legs, and lower back. These
side effects gradually disappear when treatment is over.
The side effects of chemotherapy depend mainly on the drugs that are given.
In general, anticancer drugs affect rapidly growing cells, such as blood cells
that fight infection, cells that line the digestive tract, and cells in the
hair follicles. As a result, patients can have side effects such as a lowered
resistance to infection, nausea, vomiting, or mouth sores. They can also have
less energy and may their hair.
Loss of appetite can be a problem for patients receiving radiation therapy
or chemotherapy. Researchers are learning that patients who eat well may be
better able to tolerate the side effects of their treatment. Therefore, nutrition
is an important part of the treatment plan. Eating well means getting enough
calories to prevent weight loss and having enough protein in the diet to build
and repair skin, hair, muscles, and organs. Many patients find that eating
several small meals and snacks throughout the day is easier than trying to
have three large meals.
Treatment for Hodgkin's disease can cause fertility problems. Women's menstrual
periods may stop. Periods are more likely to return in younger women. In men,
both Hodgkin's disease and its treatment can affect fertility. Younger men
are more likely to regain their fertility. Sperm banking before treatment
can be an option for some men.
The side effects that patients have during cancer therapy vary from person
to person and may even be different from one treatment to the next. Attempts
are made to plan treatment to keep problems to a minimum. Doctors, nurses,
and dietitians can explain the side effects of cancer treatment and can suggest
ways to deal with them.
INTEGRATIVE THERAPY
THE SCIENTIFICALLY FORMULATED AMINO ACID THERAPY
(Keep in mind, CAAT is much more than just a “diet”; it is an amino acid, carbohydrate, & glucose REDUCTION protocol which strategically uses the chemical reactions of amino acids, foods, and nutritional supplements to impair the development of cancer cells, thus starving them to death.) Clinical trials have already been done with humans using amino acid depravation formulas, and with much success. (Journal American Medical Association. 1967; 200:211)
CAAT is a course of therapy to control a patient’s amino acid intake. This is achieved by taking certain foods out of a persons’ daily food plan for a short time and by replacing them with a scientifically supported formula of amino acids. It is also important to emphasize that the food plan that accompanies the amino acid formula needs to be followed so not to offset any of the benefits we are creating by depriving the cancer cells the nutrients they need to grow. Also, it is important to realize that the patient does not need to abandon their conventional cancer treatment, (surgery, chemotherapy, radiation, hormone treatments) nor is it recommended that they do so unless it has already failed them. CAAT works synergistically with chemotherapy and/or radiation to enhance their benefits (see study by Dr. Marco Rabinowitz of the National Cancer Institute). His report on amino acid deprivation, such as with Controlled Amino Acid Therapy (CAAT), proven to inhibit phosphofructokinase which shuts down the energy supply to cancer cells, simultaneously enhancing the benefits of chemotherapy while lessening their toxic side effects. CAAT has also proven to work successfully alone.
Phase 1: CAAT Formulation
The most important component of CAAT is the scientifically formulated amino acids. Based on the specific formula for each cancer, it consists of separate amino acids, citric acid, and small amounts of sodium benzoate. Each formula replaces most of the regular daily proteins found in meats, dairy, fish, beans and nuts, which cancer cells can derive their energy from. The CAAT formula taken two times per day will nourish the healthy cells while causing the cancer cells to starve to death. Of course each individual has specific needs concerning their diet, and this is explained in the second phase of the protocol as well as with a specialist at the Institute when beginning the CAAT therapy.
Phase 2: Daily Food Intake
DISCLAIMER: The following food program SHOULD NOT be consumed without the amino acid formula and without consent from your doctor and our Institute.
Breakfast:
*1/2 Grapefruit or 1-orange or 6-ounces of fresh orange juice.
Whey Enhanced Protein (Vanilla Flavor – Vitamin Shoppe Brand) approximately
10 – 12 grams of protein – read label carefully, based on 150
lb. person ].
A serving of Grits (Butter, cinnamon and other spices are okay).
1 cup of green or black tea (Fructose is sweetener of choice).
* Do Not have ½ grapefruit if taking Chemotherapy
Explanation: ½ Grapefruit or 1 orange or 6 ounces of fresh orange juice are rich in the natural nutrients called Limonene and Citric Acid. Limonene helps shut down the Ras cancer gene which is over active in 90 percent of all cancers. Citric Acid helps shut down glycolosis which in turn helps starve cancer cells to death.
Whey Enhanced Protein (Vanilla Flavor – Vitamin Shoppe Brand) Phosphorus
is a nutrient that cancer cells must utilize in order to grow and reproduce.
This brand of whey protein is very low in phosphorous and contains no additional
vitamins, so when using approximately 10 – 12 grams of protein per
150 lb. person, it helps to protect normal cells, maintain a normal appetite,
and also helps to fight edema. (Edema is the swelling or water build up
in the legs or other sites in the body)
Whey protein is included in the daily menu of all advanced or metastatic
cancer patients. When treating cancers that are stable or have regressed
in size, patients then have the option of including other protein foods
at their breakfast meals such as cottage cheese, yogurt, or soy foods. Eggs
are allowed in the diets of patients with lymphoma and brain cancers.
Grits or Cream of Wheat or 1 slice of white toast or ½
plain bagel or ½ English muffin (Butter is okay)
Grits or white rice is the preferred carbohydrate food at each meal. The
other choices are options once the patient’s cancer is stable or reduced
in size. Unrefined carbohydrates are included in the CAAT menu instead of
whole grains to deprive cancer cells of a certain B-complex vitamin called
Pyridoxine (Vitamin B-6). Cancer cells require this vitamin to manufacture
certain amino acids that we keep away from through CAAT’s amino acid
reduction formula and diet.
Grits is the preferred carbohydrate food at all meals instead of rice, corn,
or pasta because it helps deplete Tryptophan in the body, which is essential
for the growth and spreading of cancer cells.
1 cup of green or black tea, using fructose as the sweetener of choice.
These teas are rich sources of several compounds that help shut down glycolosis
and cut off the energy supply to cancer cells. Also, green or regular tea
helps to prevent certain hormones and tumor growth factors from stimulating
cancer cells to grow and metastasize to other parts of the body. Brassica
teas can also be taken because they contain sulphorane, a nutrient that
inhibits cancer growth, and also shuts down the cancer genes.
* Why we use fructose as the sweetener of choice will be explained in detail
at the end of this phase of the CAAT protocol.
Lunch:
Amino acid formula (4 level plastic scoops) mixed with any of the
following: Water & Fructose; Sugar free Kool-Aid; Diet ginger ale; Fresh
lemonade & Fructose; Chicken or Beef broth; V8 juice.
Generous amounts of One cooked vegetable or a combination of the
following: asparagus, broccoli, cabbage, brussell sprouts, spinach, squash,
string beans.
One serving (1/2 cup)of fresh fruit. Choice of: pear, orange, blueberries,
raspberries, strawberries.
1 serving (moderate) of grits or corn or rice or pasta
(Add tomato sauce or butter)
1 tablespoon of coconut oil
8 to 10 black or green olives
2 tablespoons of vinegar (minimum of 5% acidity) add to vegetables or food
1 cup of green or black tea (Fructose as desired)
Explanation:
This Amino Acid Reduction Formula (4 level plastic scoops may vary) combined with the special diet, allows the CAAT Protocol to reduce certain amino acids in the daily diet of the cancer patient, and is designed to replace most of the animal protein in the diet. Cancer cells require the amino acids glycine, serine, glutamic acid, and aspartic acid to synthesize DNA, build new blood vessels or duplicate its entire contents of proteins. Also, cancer cells require these and certain other amino acids in order to synthesize other proteins that act as growth promoting hormones or tumor growth factors. CAAT impairs the synthesis of a protein called elastin, which is absolutely essential to the manufacture of new blood vessels. The Amino Acid Reduction Formula, diet, certain phytochemicals and herbs work efficaciously to attack cancer cells at each and every biological front.
The generous amounts of one cooked vegetable or a combination of such helps keep normal cells healthy. They are low in carbohydrates and proteins, and high in phytochemicals, compounds which help fight cancer. Patients are allowed to eat these vegetables and salads whenever desired.
The 8 to 10 olives are rich in squalene and oleic acid, nutrients that have been reported to inhibit certain cancer growth factors. The calories in olives also help control body weight and increases ketones in the blood. Ketones help fight cancer by impairing glycolosis – a process in which cancer cells depend almost exclusively upon for their daily supply of energy. Vinegar (and fructose) are two natural products that increase the production of both ACETIC ACID and CITRIC ACID in the body.
Acetic acid and citric acid also help fight cancer by shutting down the
process of glycolosis.
Normal cells derive most of their daily energy supply from acetic acid and
citric acid, where as cancer cells derive most of their daily energy from
glycolosis.
Dinner:
Amino acid formula (4 plastic level scoops) mixed with any of the
following: Water & fructose; Sugar free Kool–Ade; Diet Ginger
Ale; Fresh lemonade & Fructose; Chicken or Beef broth; V8 Juice.
Generous amounts of One cooked vegetable or a combination of the following:
asparagus, broccoli, cabbage, brussel sprouts, spinach, squash, string beans.
One serving (1/2 cup) of stewed plums with fresh cream & fructose; use
4-ounces of orange juice if plums are not in season.
Avacado salad with lettuce, tomatoes, celery, onions, with lemon juice and
coconut oil or olive oil.
2 tablespoons of vinegar (minimum of 5% acidity) add to vegetables or food.
1 serving of grits or corn or pasta or rice (Add garlic
and butter or tomato sauce)
1 cup of green or black tea (Fructose as desired)
Mid Evening Snack: Ketogenic Cocktail – 2 ounces of fresh
cream, ½ ounce each of both coconut & olive oil, 1 tablespoon
of Fructose.
Sugar free Jell-O with whipped cream & Fructose or 1 plum or 4 ounces
of orange juice.
Explanation: The sugar free jell-o helps to appease the appetite. Plums contain quinlic acid, which is converted into benzoic acid in the body and which in turn helps to deplete the availability of the amino acid Glycine (Glycine is essential to the synthesis of DNA for cancer cells) and the proteins that cancer cells require to build new blood vessels and their tumor growth factors. If underweight take two ounces of light cream and one ounce of olive oil/coconut oil as needed to maintain weight.
Optional Meal:
3 to 4 ounces of Veal, Fish of choice, Beef, Chicken breast, and 1-slice of white bread.
Consume this meal with a minimum of 3 hours before or after taking the amino acids.
Explanation: If the patient is 10 or more pounds underweight or if their albumin levels are below normal is when the optional meal is allowed. This meal should be eaten a minimum of 3 hours before or after taking the amino acids. CAAT provides sufficient protein to maintain the health of normal cells and adequate amounts of calories to maintain desired body weight. Any proteins taken in excess of amounts recommended in the diet will counter act the benefits of the CAAT protocol.
Special Diets: A special diet will be created for any cancer patient whose ability to consume food and liquids has placed them in a critical situation. When a patient is using a feeding apparatus, or they have become too weak or lethargic to eat and drink the daily minimum amount for survival, we will break up the total breakfast, lunch, and dinner over a period of every 2 hours during the entire day until the patient is capable of returning to a daily diet as outlined above.
Carbohydrate and glucose reduction in this diet: CAAT’S dietary menu provides approximately 20 percent of its calories in the form of carbohydrates. Calories need not be a focal point or counted daily. It is recommended that all patients combat their cancers by keeping their body weight at normal or slightly below normal levels. A patient’s desired body weight is regulated by their rate of metabolism, which in turn is regulated by their blood levels of thyroxine, cortisone, insulin, and the amounts of fats and oils in the diet. Studies with human cancer patients and laboratory animals show that reducing the calories of carbohydrates (glucose) in their daily diet by only 10 percent reduced the size of cancerous tumors. When carbohydrate (glucose) calories were reduced 40 percent, the cancers disappeared. It is recommended that those patients who are obese gradually and systematically lose their excess weight to increase the efficiency of the CAAT protocol. Those patients who are underweight shoudn’t gain weight unless they are more than 10 pounds below normal levels. When a patient is underweight due to anorexia or cachexia, such illnesses must be addressed before the CAAT protocol can begin.
Why we use Fructose and Vinegar to treat cancer:
Nobel Prize winner Dr. Otto Warburg discovered more than 50 years ago that all cancer cells produce inordinate amount of lactic acid but he couldn’t explain why.
In 2001 our Institute published the first study to show that cancer cells produce excess amounts of lactic acid because they could not access the oxygen in compartments in the cells called the mitochondria. This provided evidence that cancer cells depend almost exclusively upon glycolosis or the metabolism of glucose as their major source of energy.
Dr. Spitz and Dr. Lee with other cancer researchers published studies showing that when cancer cells are deprived glucose, their energy supply is cut off which causes these cancer cells to commit suicide.
Therefore shutting down glycolosis would be one means of destroying cancer cells because energy can only be derived from glucose through the metabolic process called glycolosis.
Recently our Cancer Institute discovered that both acetic acid and citric acid could inhibit the activity of a key enzyme in glycolosis called phosphofructokinase, which in turn shuts down the process of glycolosis. Our cancer Institute is the first to introduce both fructose and vinegar as treatments for cancer because they either contain or produce acetic acid.
In conclusion, fructose and vinegar are added as supplements to the CAAT protocol because of their acetic acid properties that help shut down glycolosis, shutting off cancer cells energy supply and causing them to die off.
Phase 3: Nutritional Supplements
Nutritional supplements are based on each unique situation. For example, slow-growing cancers produce low levels of toxic free radicals. Tumor cells that grow aggressively produce large amounts of toxic free radicals. The patient will be instructed whether or not to take anti-oxidants (in a nutritional supplement), and at what dosage, according to the levels of toxic free radicals produced in the cancerous cells.
An example of how nutritional supplements can help manipulate cancer cells involves vitamin B-6 (pyroxidine) There are four amino acids essential to the synthesis of DNA. However, those amino acids cannot be synthesized without a certain enzyme, which includes vitamin B-6 among other components. Any supplement containing vitamin B-6 SHOULD NOT be taken during the first 2 months of the CAAT protocol.
The patient will be instructed as to which nutritional supplements or phytochemicals should be purchased and at what dosage strength. Keep in mind that each supplement only complements the CAAT protocol. However, when they are combined they augment the therapeutic benefits of the aminoacid, carbohydrate, and glucose reduction diet.
Parsley: Contains ingredients that can help shut down certain enzymes called Epithelial Growth Factors, which stimulate the growth and spread of cancer. ( CAAT’S amino acid reduction diet works in the same manner )
Vitamin D: Helps activate in many kinds of cancers enzymes called Phosphotases, which literally shut down the activities of other enzymes called Kinases, which are essential to the growth and reproduction of cancer cells.
Green Tea Extract: Phytochemicals in tea help shut down glycolosis (cancer cell’s main supplier of energy) and thereby help to starve cancer cells to death. These effects help complement the effects of CAAT’S carbohydrate reduction.
Anti-Oxidants: The controversy as to whether or not to treat cancer with anti-oxidants is slowly resolving with the current understanding of how they affect the activity of genes and enzymes in cancer cells. The prevailing data shows that the benefits or lack of benefits depend upon the oxidative state the cancer cells are in. Anti-oxidants taken when the cells are in a very high oxidative state may prevent cancer cells from entering apoptosis ( apoptosis is when a cancer cell commits suicide) When oxidative stress in cancer cells is only slightly above normal, anti-oxidants are then expected to stop their growth and reproduction.
Blood Chemistry: Blood tests are usually taken every 6 to 8 weeks, depending upon the results of each test. Not only is it important to monitor the tumor markers but equally important to keep abreast of the overall health of normal tissues and organs. For example, it is important to learn of the health of the kidneys and liver, whether the body is producing sufficient red and white blood cells, etc. Low albumin levels most often indicate insufficient intake of proteins in the diet and this problem would have to be addressed. CAAT is designed to attack cancer but keep the normal cells and tissues functioning harmoniously.
Whey Protein: This protein food is recommended at the breakfast meal to help meet the daily needs of amino acids for the normal cells of the body, and to help keep albumin levels normal and to help prevent edema. We recommend Whey protein purchased from the Vitamin Shoppe because it is the only brand that we have seen with no phosphorous or additional vitamins added to it.
Grits: Grits are also recommended at the breakfast meal in place of whole grains because it is low in vitamin B-6. Cancer cells require B-6 to manufacture the amino acid Glycine, which is required for DNA synthesis. Grits, instead of whole grains, therefore helps prevent cancer cells from manufacturing DNA and building new blood vessels.
Calcium D-Glucurate: This phytochemical helps the body to retain a compound called Glucuronic acid. This is necessary to eliminate both estrogen and testosterone from the body. This is why Calcium D-Glucurate is added to the regiments of patients with breast & prostate cancers. Calcium D-Glucurate is not to be confused with calcium carbonate, which is nothing more than a calcium supplement.
D-Limonene: This phytochemical found mostly in citrus fruits blocks the process called Isoprenylation, which is necessary for tumor growth factors such as the RAS gene, Epithelial Growth factor, Tyrosine Kinase, and Insulin-Like-Growth-factor, to send their signals into the nucleus of a cancer cell and directs them to grow and divide into more cancer cells.
Tocotrienols: This member of the Vitamin E family also helps shut down Isoprenylation and assists D-Limonene in blocking the actions of the various tumor growth factors. More specifically, tocotrienols shut down an enzyme called HMG-2, which is essential to the synthesis of the building blocks that form the Isoprenylation process.
Niacin: This B-Complex vitamin works with D-limonene and the Tocotrienols to shut down the process of Isoprenylation, which as mentioned above prevents the cancer promoting RAS genes from sending signals into the nucleus of the cell. Niacin also helps deplete thee amino acid Glycine, which cancer cells need to synthesize DNA. And by reducing cholesterole in the body, Niacin helps lower the production of estrogen and testosterone.
Choline: This B-complex vitamin is included in our supplement list to help the liver metabolize Niacin and other compounds and to help fight fatigue that accompanies most forms of cancer.
Selenium: Numerous studies show that this mineral can interfere with the activity of certain genes that promote the growth of cancer and to induce cancer cells to commit suicide (apoptosis)
Perilla Oil: This oil is rich in Alpha Linolenic Acid which can inhibit the growth of cancer cells in several ways. One way is to inhibit the synthesis in the body of a tumor growth promotin hormone called Prostaglandin-2, also, Alpha Linolenic Acid inhibits the actions of certain genes that promote the growth of cancer cells. Linolenic acid is not to be confused with linoleic acid, which is a bad fat that stimulates the growth of cancer cells. This bad fat, linoleic acid, is found in all vegetable oils and nuts (With the exception of coconut oil). Olive oil has the least amount of this bad fat.
Super Miraforte: This herb impairs the synthesis of estrogen from
testosterone in the body and is included in the regiments of women with
breast cancer.
Licorice Root Extract & Pantothenic Acid: This herb and vitamin are
added to the regiment when it is desirable to produce steroid like actions
in the body. Also used to help patient’s gain weight and to inhibit
the growth of lymphomas and leukemia’s.
Resveratrol: This phytochemical blocks the actions of a number of a number of cancer promoting genes thereby causing cancer cells to enter into apoptosis (cell death) and is included in the treatment of all cancers.
Indole-3 Carbinol & D.I.M.: These two phytochemicals block the actions of both estrogen and testosterone and are included in the regiments of both breast and prostate gland cancer.
Melatonin: Numerous studies show that this hormone blocks the synthesis of the cancer promoting chemicals in the body called Leukotrienes, and is included in the treatment of all cancers.
Artho Pro System: This combination of herbs and phytochemicals inhibits the synthesis of the cancer promoting hormone called Prostaglandin-2 and the Leukotriens and replaces the drug celebrex when liver problems are present. The Prostaglandin hormone is over active in most cancers and stimulates cancer growth. The body manufactures the Prostaglandin hormone from the bad fat, Linoleic acid, mentioned above.
Licorice Root Extract & Pantothenic Acid: This HERB and
VITAMIN are added to the regiment when it is desirable to produce
steroid like actions in the body. Used also to help patients gain weight
and ti inhibit the growth of Lymphomas and Leukemias.
CAAT is designed to attack cancer, while keeping normal cells and tissues functioning harmoniously.
* When considering any type of complementary cancer treatment or alternative cancer treatment, always consult with your physician first, as possible interactions could reduce your regimen’s efficacy.
| If this information has generated any questions you would like answered. |
