Kidney Cancer
What is Kidney Cancer?
Kidney cancer is a disease of the kidneys, the reddish-brown curving organs about the size of a small fist, located above the waist to either side of the spine. They are closer to the back of the body than to the front. In kidney cancer, cells grow unregulated by the signals that normally regulate cell growth and death, and form tumors.
Kidneys filter blood and remove impurities, excess minerals and salts, and surplus water. Every day, they process about 200 quarts of blood to generate two quarts of urine. These organs also produce hormones to help control blood pressure, red blood cell production, and other functions. Although people have two kidneys, each works independently. The human body can function with less than one complete kidney. With dialysis, a mechanized filtering process, it is possible to live without kidneys.
There are several types of kidney
cancers:
Renal cell carcinomas
comprise about 85% of kidney cancers. This cancer develops
within the kidney's microscopic filtering systems, in the lining of tiny
tubules.
Transitional cell
carcinoma begins in the area of the kidney where urine
collects before being funneled to the bladder. This type of kidney cancer is
similar to bladder cancer and is treated like bladder cancer.
Wilm's
tumor, found most often in children, is also treated
differently from adult kidney cancer.
Knowing which kind of cell a tumor is composed of helps doctors
plan treatment. In kidney cancer, there are four types, of which two are
notable: "clear cell" is the kind found in 80% of kidney cancer, and
"sarcomatoid" is the most aggressive type.
Surgery to remove a kidney tumor, or the kidney itself, provides a
reasonable chance of cure if the cancer has not spread beyond the confines of
the organ. If it has metastasized, kidney cancer is difficult to treat with
traditional therapies. Since one percent of all kidney cancers spontaneously
shrink or disappear, scientists have focused on the body's immune system as a
useful tool to treat advanced kidney cancer.
Kidney Cancer: Who's at Risk?
Research has shown that people with certain risk factors are more likely than others to develop kidney cancer. A risk factor is anything that increases a person's chance of developing a disease.
Studies have found the following risk factors for kidney cancer:
- Smoking: Cigarette smoking is a major risk factor. Cigarette smokers are twice as likely as nonsmokers to develop kidney cancer. Cigar smoking also may increase the risk of this disease.
- Obesity: People who are obese have an increased risk of kidney cancer.
- High blood pressure: High blood pressure increases the risk of kidney cancer.
- Long-term dialysis: Dialysis is a treatment for people whose kidneys do not work well. It removes wastes from the blood. Being on dialysis for many years is a risk factor for kidney cancer.
- Von Hippel-Lindau (VHL) syndrome: VHL is a rare disease that runs in some families. It is caused by changes in the VHL gene. An abnormal VHL gene increases the risk of kidney cancer. It also can cause cysts or tumors in the eyes, brain, and other parts of the body. Family members of those with this syndrome can have a test to check for the abnormal VHL gene. For people with the abnormal VHL gene, doctors may suggest ways to improve the detection of kidney cancer and other diseases before symptoms develop.
- Occupation: Some people have a higher risk of getting kidney cancer because they come in contact with certain chemicals or substances in their workplace. Coke oven workers in the iron and steel industry are at risk. Workers exposed to asbestos or cadmium also may be at risk.
- Gender: Males are more likely than females to be diagnosed with kidney cancer. Each year in the United States, about 20,000 men and 12,000 women learn they have kidney cancer.
Possible signs of renal cell cancer include blood in the urine and a lump in the abdomen.
These and other symptoms may be caused by renal cell cancer or by other conditions. There may be no symptoms in the early stages. Symptoms may appear as the tumor grows. A doctor should be consulted if any of the following problems occur:
- Blood in the urine.
- A lump in the abdomen.
- A pain in the side that doesn't go away.
- Loss of appetite.
- Weight loss for no known reason.
- Anemia.
What are the symptoms of kidney cancer?
The most common symptom of kidney cancer is blood in the urine. In some cases,
a person can actually see the blood. It may be present one day and not the
next. Traces of blood may also be found in urinalysis, a urine test done as
part of a regular medical checkup.
Another symptom of kidney cancer is a lump or mass that can be felt in the
kidney area. The tumor may cause a dull ache or pain in the back or side.
Less often, signs of a kidney tumor include high blood pressure or an abnormal
number of red blood cells.
Symptoms may develop suddenly. However, as with other types of cancer, kidney
cancer can cause a general feeling of poor health. People with this disease
may feel tired, lose their appetite, and lose weight. Some have a fever that
comes and goes. These symptoms may be caused by cancer or by other, less serious
problems such as an infection or a fluid-filled cyst. A doctor is consulted
for a definite diagnosis.
Tests that examine the abdomen and kidneys are used to detect (find) and diagnose
renal cell cancer.
The following tests and procedures may be used:
- Physical exam and history: An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patient’s health habits and past illnesses and treatments will also be taken.
- Blood chemistry studies: A procedure in which a blood sample is checked to measure the amounts of certain substances released into the blood by organs and tissues in the body. An unusual (higher or lower than normal) amount of a substance can be a sign of disease in the organ or tissue that produces it.
- Urinalysis: A test to check the color of urine and its contents, such as sugar, protein, blood, and bacteria.
- Liver function test: A procedure in which a sample of blood is checked to measure the amounts of enzymes released into it by the liver. An abnormal amount of an enzyme can be a sign that cancer has spread to the liver. Certain conditions that are not cancer may also increase liver enzyme levels.
- Intravenous pyelogram (IVP): A series of x-rays of the kidneys, ureters, and bladder to find out if cancer is present in these organs. A contrast dye is injected into a vein. As the contrast dye moves through the kidneys, ureters, and bladder, x-rays are taken to see if there are any blockages.
- Ultrasound: A procedure in which high-energy sound waves (ultrasound) are bounced off internal tissues or organs and make echoes. The echoes form a picture of body tissues called a sonogram.
- CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.
- MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the body. This procedure is also called nuclear magnetic resonance imaging (NMRI).
- Biopsy: The removal of cells or tissues so they can be viewed under a microscope to check for signs of cancer. A thin needle is inserted into the tumor and a sample of tissue is withdrawn. A pathologist then views the tissue under a microscope to check for cancer cells.
The prognosis (chance of recovery) and treatment options depend on the following:
- The stage of the disease.
- The patient's age and general health.
Healthy Cells vs. Cancer Cells
Healthy cells are like a cat. They need
structure to determine the size of bones and shape of
the body, tail and whiskers. The DNA in genes and chromosomes determine this.
They need energy to play and prowl and sustain life. This is derived from
chemicals in food. Cats need a system to deliver chemicals (food nutrients like
amino acids, carbohydrates, fats, vitamins and minerals) to all parts of their
body. These are the blood vessels. Growth
factors take a kitten into a lazy old cat, all the while
helping it to function normally.
The body and its cells are mostly made up of protein. The building
blocks of proteins are substances called amino acids that in the form of enzymes
and hormones literally control every chemical reaction within the cells. When
these are modified, different messages are sent to a complex control system that
can alter their function. There are twenty different kinds of amino acids that
are essential to life. Twelve of these can be synthesized within the body
however; eight must be supplied by the daily diet.
|
Structure |
|
|
Normal
Cells |
Cancer
Cells |
|
DNA in genes and chromosomes go about their business in a normal
way. |
Cancer cells develop a different DNA or gene structure or acquire
abnormal numbers of chromosomes. |
|
Cells divide in an orderly way to produce more cells only when the
body needs them. |
Cells continue to be created without control or order.
If not needed, a mass of tissue is formed which is called a
tumor. |
|
Energy |
|
|
Normal
Cells |
Cancer
Cells |
|
Cells derive 70% of their energy from a system called the “Krebs
Cycle.” |
Cells have a defective “Krebs Cycle” and derive little or no energy
from it. |
|
Cells derive only 20% of their energy from a system called
“Glycolosis.” |
Cancer cells derive almost all their energy from
“Glycolosis.” |
|
Cells derive most of their energy with the use of
oxygen. |
Cells derive most of their energy in the absence of
oxygen. |
|
Blood
Vessels |
|
|
Normal
Cells |
Cancer
Cells |
|
Cells have a built-in blood vessel
system. |
Cells do not have a built-in blood vessel system.
They require more of certain amino acids to
grow. |
|
Growth
Factors |
|
|
Normal
Cells |
Cancer
Cells |
|
While similar to cancer cells, the amount of them is more in
balance to produce a more normal level of
activity. |
These cells have over produced, require more chemicals (food) and
are over active. |
|
Functions |
|
|
Normal
Cells |
Cancer
Cells |
|
The enzymes and hormones go about business in a normal balanced
manner. |
The enzymes and hormones are either over active or under
active. |
|
Tumors are
Different |
|
|
Benign |
Malignant |
|
Benign tumors are not cancerous. They do not invade
nearby tissues nor spread to other parts of the body. They can be
removed and are not a threat to life. |
Malignant tumors are cancerous. They can invade and
damage nearby tissues and organs and they can break away and enter the blood
stream to form new tumors in other parts of the body. The spread of cancer is
called metastasis. |
After renal cell cancer has been diagnosed, tests are done to find out
if cancer cells have spread within the kidney or to other parts of the body.
The process used to find out if cancer has spread within the kidney
or to other parts of the body is called staging. The information gathered
from the staging process determines the stage of the disease. It is
important to know the stage in order to plan treatment. The following tests
and procedures may be used in the staging process:
- CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.
- MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the body. This procedure is also called nuclear magnetic resonance imaging (NMRI).
- Chest x-ray: An x-ray of the organs and bones inside the chest. An x-ray is a type of energy beam that can go through the body and onto film, making a picture of areas inside the body.
- Bone scan: A procedure to check if there are rapidly dividing cells, such as cancer cells, in the bone. A very small amount of radioactive material is injected into a vein and travels through the bloodstream. The radioactive material collects in the bones and is detected by a scanner.
Stage I
In stage I, the tumor is no larger than 7 centimeters and is found in the kidney only.
Stage I Renal Cell Cancer
Standard treatment of stage I renal cell cancer may include the following:
- Surgery (radical nephrectomy, simple nephrectomy, or partial nephrectomy).
- Radiation therapy as palliative therapy to relieve symptoms in patients who cannot have surgery.
- Arterial embolization as palliative therapy.
In stage II, the tumor is larger than 7 centimeters and is found in the kidney only.
Stage II Renal Cell Cancer
Standard treatment of stage II renal cell cancer may include the following:
- Surgery (radical nephrectomy or partial nephrectomy).
- Surgery (nephrectomy), before or after radiation therapy.
- Radiation therapy as palliative therapy to relieve symptoms in patients who cannot have surgery.
- Arterial embolization as palliative therapy.
In stage III, cancer is found:
- in the kidney and in 1 nearby lymph node; or
- in an adrenal gland or in the layer of fatty tissue around the kidney, and may be found in 1 nearby lymph node; or
- in the main blood vessels of the kidney and may be found in 1 nearby lymph node.
Standard treatment of stage III renal cell cancer may include the following:
- Surgery (radical nephrectomy). Blood vessels of the kidney and some lymph nodes may also be removed.
- Arterial embolization followed by surgery (radical nephrectomy).
- Radiation therapy as palliative therapy to relieve symptoms and improve the quality of life.
- Arterial embolization as palliative therapy.
- Surgery (nephrectomy) as palliative therapy.
- Radiation therapy before or after surgery (radical nephrectomy).
In stage IV, cancer has spread:
- beyond the layer of fatty tissue around the kidney and may be found in 1 nearby lymph node; or
- to 2 or more nearby lymph nodes; or
- to other organs, such as the bowel, pancreas, or lungs, and may be found in nearby lymph nodes.
Standard treatment of stage IV renal cell cancer may include the following:
- Biologic therapy.
- Radiation therapy as palliative therapy to relieve symptoms and improve the quality of life.
- Surgery (nephrectomy) as palliative therapy.
- Surgery (radical nephrectomy, with or without removal of cancer from other areas where it has spread).
Different types of treatments are available for patients with renal cell cancer. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. Before starting treatment, patients may want to think about taking part in a clinical trial. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment.
Four types of standard treatment are used:
1. Surgery
Surgery to remove part or all of the kidney is often used to treat renal cell cancer. The following types of surgery may be used:
- Partial nephrectomy: A surgical procedure to remove the cancer within the kidney and some of the tissue around it. A partial nephrectomy may be done to prevent loss of kidney function when the other kidney is damaged or has already been removed.
- Simple nephrectomy: A surgical procedure to remove the kidney only.
- Radical nephrectomy: A surgical procedure to remove the kidney, the adrenal gland, surrounding tissue, and, usually, nearby lymph nodes.
When surgery to remove the cancer is not possible, a treatment called arterial embolization may be used to shrink the tumor. A small incision is made and a catheter (thin tube) is inserted into the main blood vessel that flows to the kidney. Small pieces of a special gelatin sponge are injected through the catheter into the blood vessel. The sponges block the blood flow to the kidney and prevent the cancer cells from getting oxygen and other substances they need to grow.
Even if the doctor removes all the cancer that can be seen at the time of the surgery, some patients may be given chemotherapy or radiation therapy after surgery to kill any cancer cells that are left. Treatment given after the surgery, to increase the chances of a cure, is called adjuvant therapy.
2. Radiation therapy
Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells. There are 2 types of radiation therapy. External radiation therapy uses a machine outside the body to send radiation toward the cancer. Internal radiation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer. The way the radiation therapy is given depends on the type and stage of the cancer being treated.
3. Chemotherapy
Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping the cells from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the spinal column, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated.
What are the side effects of treatment for kidney cancer?
The methods used to treat kidney cancer are very powerful. It is hard to
limit the effects of treatment so that only cancer cells are destroyed; healthy
cells may also be damaged. That is why treatment often causes unpleasant side
effects. Side effects depend on the type of treatment and the part of the
body being treated.
Nephrectomy is major surgery. For a few days after the operation, most patients
need medicine to relieve pain. Discomfort may make it difficult to breathe
deeply, and patients have to do special coughing and breathing exercises to
keep their lungs clear. Patients may need IV (intravenous) feedings and fluids
for several days before and after the operation. Nurses will keep track of
the amount of fluid the patient takes in and the amount of urine produced.
The remaining kidney takes over the work of the one that was removed.
Embolization can cause pain, fever, nausea, or vomiting. These problems are
treated with medicine. Often, patients also require intravenous fluids.
During radiation therapy, the patient may become very tired as the treatment
continues. Resting as much as possible is important. Skin reactions (redness
or dryness) in the treated area are also common, and the skin should be protected
from the sun. Good skin care is important at this time, but the patient should
not use any lotion or cream on the skin without consulting the doctor. Radiation
therapy can cause nausea, vomiting, and diarrhea. Usually, certain foods and
medicines can ease these problems.
The side effects of hormone therapy are usually mild. Progesterone is the
hormone most often used to treat kidney cancer. Drugs containing progesterone
generally cause few side effects, though some patients may retain fluid and
gain weight.
The side effects caused by biological therapies vary with the type of treatment.
Often, these treatments cause flu-like symptoms such as chills, fever, muscle
aches, weakness, loss of appetite, nausea, vomiting, and diarrhea. Sometimes,
patients develop a rash with dry, itching skin. Patients often feel very tired
after treatment. In addition, interleukin-2 can cause the patient to retain
fluid. These problems can be severe, and most patients need to stay in the
hospital during treatment.
Loss of appetite can be a serious problem for patients during their treatment
for cancer. Patients who eat well may be better able to withstand the side
effects of their treatment, so good nutrition is an important part of the
treatment plan. Eating well means getting enough calories to prevent weight
loss and having enough protein to regain strength and rebuild normal tissues.
Many patients find that eating several small meals and snacks during the day
works better than trying to have three large meals.
The side effects that patients have during cancer treatment vary for each
person. They may be different from one treatment to the next. Attempts are
made to plan therapy to minimize problems. Fortunately, most side effects
are temporary. Doctors, nurses, and dietitians can explain the side effects
of cancer treatment and can suggest ways to deal with them.
INTEGRATIVE THERAPY
THE SCIENTIFICALLY FORMULATED AMINO ACID THERAPY
(Keep in mind, CAAT is much more than just a “diet”; it is an amino acid, carbohydrate, & glucose REDUCTION protocol which strategically uses the chemical reactions of amino acids, foods, and nutritional supplements to impair the development of cancer cells, thus starving them to death.) Clinical trials have already been done with humans using amino acid depravation formulas, and with much success. (Journal American Medical Association. 1967; 200:211)
CAAT is a course of therapy to control a patient’s amino acid intake. This is achieved by taking certain foods out of a persons’ daily food plan for a short time and by replacing them with a scientifically supported formula of amino acids. It is also important to emphasize that the food plan that accompanies the amino acid formula needs to be followed so not to offset any of the benefits we are creating by depriving the cancer cells the nutrients they need to grow. Also, it is important to realize that the patient does not need to abandon their conventional cancer treatment, (surgery, chemotherapy, radiation, hormone treatments) nor is it recommended that they do so unless it has already failed them. CAAT works synergistically with chemotherapy and/or radiation to enhance their benefits (see study by Dr. Marco Rabinowitz of the National Cancer Institute). His report on amino acid deprivation, such as with Controlled Amino Acid Therapy (CAAT), proven to inhibit phosphofructokinase which shuts down the energy supply to cancer cells, simultaneously enhancing the benefits of chemotherapy while lessening their toxic side effects. CAAT has also proven to work successfully alone.
Phase 1: CAAT Formulation
The most important component of CAAT is the scientifically formulated amino acids. Based on the specific formula for each cancer, it consists of separate amino acids, citric acid, and small amounts of sodium benzoate. Each formula replaces most of the regular daily proteins found in meats, dairy, fish, beans and nuts, which cancer cells can derive their energy from. The CAAT formula taken two times per day will nourish the healthy cells while causing the cancer cells to starve to death. Of course each individual has specific needs concerning their diet, and this is explained in the second phase of the protocol as well as with a specialist at the Institute when beginning the CAAT therapy.
Phase 2: Daily Food Intake
DISCLAIMER: The following food program SHOULD NOT be consumed without the amino acid formula and without consent from your doctor and our Institute.
Breakfast:
*1/2 Grapefruit or 1-orange or 6-ounces of fresh orange juice.
Whey Enhanced Protein (Vanilla Flavor – Vitamin Shoppe Brand) approximately
10 – 12 grams of protein – read label carefully, based on 150
lb. person ].
A serving of Grits (Butter, cinnamon and other spices are okay).
1 cup of green or black tea (Fructose is sweetener of choice).
* Do Not have ½ grapefruit if taking Chemotherapy
Explanation: ½ Grapefruit or 1 orange or 6 ounces of fresh orange juice are rich in the natural nutrients called Limonene and Citric Acid. Limonene helps shut down the Ras cancer gene which is over active in 90 percent of all cancers. Citric Acid helps shut down glycolosis which in turn helps starve cancer cells to death.
Whey Enhanced Protein (Vanilla Flavor – Vitamin Shoppe Brand) Phosphorus
is a nutrient that cancer cells must utilize in order to grow and reproduce.
This brand of whey protein is very low in phosphorous and contains no additional
vitamins, so when using approximately 10 – 12 grams of protein per
150 lb. person, it helps to protect normal cells, maintain a normal appetite,
and also helps to fight edema. (Edema is the swelling or water build up
in the legs or other sites in the body)
Whey protein is included in the daily menu of all advanced or metastatic
cancer patients. When treating cancers that are stable or have regressed
in size, patients then have the option of including other protein foods
at their breakfast meals such as cottage cheese, yogurt, or soy foods. Eggs
are allowed in the diets of patients with lymphoma and brain cancers.
Grits or Cream of Wheat or 1 slice of white toast or ½
plain bagel or ½ English muffin (Butter is okay)
Grits or white rice is the preferred carbohydrate food at each meal. The
other choices are options once the patient’s cancer is stable or reduced
in size. Unrefined carbohydrates are included in the CAAT menu instead of
whole grains to deprive cancer cells of a certain B-complex vitamin called
Pyridoxine (Vitamin B-6). Cancer cells require this vitamin to manufacture
certain amino acids that we keep away from through CAAT’s amino acid
reduction formula and diet.
Grits is the preferred carbohydrate food at all meals instead of rice, corn,
or pasta because it helps deplete Tryptophan in the body, which is essential
for the growth and spreading of cancer cells.
1 cup of green or black tea, using fructose as the sweetener of choice.
These teas are rich sources of several compounds that help shut down glycolosis
and cut off the energy supply to cancer cells. Also, green or regular tea
helps to prevent certain hormones and tumor growth factors from stimulating
cancer cells to grow and metastasize to other parts of the body. Brassica
teas can also be taken because they contain sulphorane, a nutrient that
inhibits cancer growth, and also shuts down the cancer genes.
* Why we use fructose as the sweetener of choice will be explained in detail
at the end of this phase of the CAAT protocol.
Lunch:
Amino acid formula (4 level plastic scoops) mixed with any of the
following: Water & Fructose; Sugar free Kool-Aid; Diet ginger ale; Fresh
lemonade & Fructose; Chicken or Beef broth; V8 juice.
Generous amounts of One cooked vegetable or a combination of the
following: asparagus, broccoli, cabbage, brussell sprouts, spinach, squash,
string beans.
One serving (1/2 cup)of fresh fruit. Choice of: pear, orange, blueberries,
raspberries, strawberries.
1 serving (moderate) of grits or corn or rice or pasta
(Add tomato sauce or butter)
1 tablespoon of coconut oil
8 to 10 black or green olives
2 tablespoons of vinegar (minimum of 5% acidity) add to vegetables or food
1 cup of green or black tea (Fructose as desired)
Explanation:
This Amino Acid Reduction Formula (4 level plastic scoops may vary) combined with the special diet, allows the CAAT Protocol to reduce certain amino acids in the daily diet of the cancer patient, and is designed to replace most of the animal protein in the diet. Cancer cells require the amino acids glycine, serine, glutamic acid, and aspartic acid to synthesize DNA, build new blood vessels or duplicate its entire contents of proteins. Also, cancer cells require these and certain other amino acids in order to synthesize other proteins that act as growth promoting hormones or tumor growth factors. CAAT impairs the synthesis of a protein called elastin, which is absolutely essential to the manufacture of new blood vessels. The Amino Acid Reduction Formula, diet, certain phytochemicals and herbs work efficaciously to attack cancer cells at each and every biological front.
The generous amounts of one cooked vegetable or a combination of such helps keep normal cells healthy. They are low in carbohydrates and proteins, and high in phytochemicals, compounds which help fight cancer. Patients are allowed to eat these vegetables and salads whenever desired.
The 8 to 10 olives are rich in squalene and oleic acid, nutrients that have been reported to inhibit certain cancer growth factors. The calories in olives also help control body weight and increases ketones in the blood. Ketones help fight cancer by impairing glycolosis – a process in which cancer cells depend almost exclusively upon for their daily supply of energy. Vinegar (and fructose) are two natural products that increase the production of both ACETIC ACID and CITRIC ACID in the body.
Acetic acid and citric acid also help fight cancer by shutting down the
process of glycolosis.
Normal cells derive most of their daily energy supply from acetic acid and
citric acid, where as cancer cells derive most of their daily energy from
glycolosis.
Dinner:
Amino acid formula (4 plastic level scoops) mixed with any of the
following: Water & fructose; Sugar free Kool–Ade; Diet Ginger
Ale; Fresh lemonade & Fructose; Chicken or Beef broth; V8 Juice.
Generous amounts of One cooked vegetable or a combination of the following:
asparagus, broccoli, cabbage, brussel sprouts, spinach, squash, string beans.
One serving (1/2 cup) of stewed plums with fresh cream & fructose; use
4-ounces of orange juice if plums are not in season.
Avacado salad with lettuce, tomatoes, celery, onions, with lemon juice and
coconut oil or olive oil.
2 tablespoons of vinegar (minimum of 5% acidity) add to vegetables or food.
1 serving of grits or corn or pasta or rice (Add garlic
and butter or tomato sauce)
1 cup of green or black tea (Fructose as desired)
Mid Evening Snack: Ketogenic Cocktail – 2 ounces of fresh
cream, ½ ounce each of both coconut & olive oil, 1 tablespoon
of Fructose.
Sugar free Jell-O with whipped cream & Fructose or 1 plum or 4 ounces
of orange juice.
Explanation: The sugar free jell-o helps to appease the appetite. Plums contain quinlic acid, which is converted into benzoic acid in the body and which in turn helps to deplete the availability of the amino acid Glycine (Glycine is essential to the synthesis of DNA for cancer cells) and the proteins that cancer cells require to build new blood vessels and their tumor growth factors. If underweight take two ounces of light cream and one ounce of olive oil/coconut oil as needed to maintain weight.
Optional Meal:
3 to 4 ounces of Veal, Fish of choice, Beef, Chicken breast, and 1-slice of white bread.
Consume this meal with a minimum of 3 hours before or after taking the amino acids.
Explanation: If the patient is 10 or more pounds underweight or if their albumin levels are below normal is when the optional meal is allowed. This meal should be eaten a minimum of 3 hours before or after taking the amino acids. CAAT provides sufficient protein to maintain the health of normal cells and adequate amounts of calories to maintain desired body weight. Any proteins taken in excess of amounts recommended in the diet will counter act the benefits of the CAAT protocol.
Special Diets: A special diet will be created for any cancer patient whose ability to consume food and liquids has placed them in a critical situation. When a patient is using a feeding apparatus, or they have become too weak or lethargic to eat and drink the daily minimum amount for survival, we will break up the total breakfast, lunch, and dinner over a period of every 2 hours during the entire day until the patient is capable of returning to a daily diet as outlined above.
Carbohydrate and glucose reduction in this diet: CAAT’S dietary menu provides approximately 20 percent of its calories in the form of carbohydrates. Calories need not be a focal point or counted daily. It is recommended that all patients combat their cancers by keeping their body weight at normal or slightly below normal levels. A patient’s desired body weight is regulated by their rate of metabolism, which in turn is regulated by their blood levels of thyroxine, cortisone, insulin, and the amounts of fats and oils in the diet. Studies with human cancer patients and laboratory animals show that reducing the calories of carbohydrates (glucose) in their daily diet by only 10 percent reduced the size of cancerous tumors. When carbohydrate (glucose) calories were reduced 40 percent, the cancers disappeared. It is recommended that those patients who are obese gradually and systematically lose their excess weight to increase the efficiency of the CAAT protocol. Those patients who are underweight shoudn’t gain weight unless they are more than 10 pounds below normal levels. When a patient is underweight due to anorexia or cachexia, such illnesses must be addressed before the CAAT protocol can begin.
Why we use Fructose and Vinegar to treat cancer:
Nobel Prize winner Dr. Otto Warburg discovered more than 50 years ago that all cancer cells produce inordinate amount of lactic acid but he couldn’t explain why.
In 2001 our Institute published the first study to show that cancer cells produce excess amounts of lactic acid because they could not access the oxygen in compartments in the cells called the mitochondria. This provided evidence that cancer cells depend almost exclusively upon glycolosis or the metabolism of glucose as their major source of energy.
Dr. Spitz and Dr. Lee with other cancer researchers published studies showing that when cancer cells are deprived glucose, their energy supply is cut off which causes these cancer cells to commit suicide.
Therefore shutting down glycolosis would be one means of destroying cancer cells because energy can only be derived from glucose through the metabolic process called glycolosis.
Recently our Cancer Institute discovered that both acetic acid and citric acid could inhibit the activity of a key enzyme in glycolosis called phosphofructokinase, which in turn shuts down the process of glycolosis. Our cancer Institute is the first to introduce both fructose and vinegar as treatments for cancer because they either contain or produce acetic acid.
In conclusion, fructose and vinegar are added as supplements to the CAAT protocol because of their acetic acid properties that help shut down glycolosis, shutting off cancer cells energy supply and causing them to die off.
Phase 3: Nutritional Supplements
Nutritional supplements are based on each unique situation. For example, slow-growing cancers produce low levels of toxic free radicals. Tumor cells that grow aggressively produce large amounts of toxic free radicals. The patient will be instructed whether or not to take anti-oxidants (in a nutritional supplement), and at what dosage, according to the levels of toxic free radicals produced in the cancerous cells.
An example of how nutritional supplements can help manipulate cancer cells involves vitamin B-6 (pyroxidine) There are four amino acids essential to the synthesis of DNA. However, those amino acids cannot be synthesized without a certain enzyme, which includes vitamin B-6 among other components. Any supplement containing vitamin B-6 SHOULD NOT be taken during the first 2 months of the CAAT protocol.
The patient will be instructed as to which nutritional supplements or phytochemicals should be purchased and at what dosage strength. Keep in mind that each supplement only complements the CAAT protocol. However, when they are combined they augment the therapeutic benefits of the aminoacid, carbohydrate, and glucose reduction diet.
Parsley: Contains ingredients that can help shut down certain enzymes called Epithelial Growth Factors, which stimulate the growth and spread of cancer. ( CAAT’S amino acid reduction diet works in the same manner )
Vitamin D: Helps activate in many kinds of cancers enzymes called Phosphotases, which literally shut down the activities of other enzymes called Kinases, which are essential to the growth and reproduction of cancer cells.
Green Tea Extract: Phytochemicals in tea help shut down glycolosis (cancer cell’s main supplier of energy) and thereby help to starve cancer cells to death. These effects help complement the effects of CAAT’S carbohydrate reduction.
Anti-Oxidants: The controversy as to whether or not to treat cancer with anti-oxidants is slowly resolving with the current understanding of how they affect the activity of genes and enzymes in cancer cells. The prevailing data shows that the benefits or lack of benefits depend upon the oxidative state the cancer cells are in. Anti-oxidants taken when the cells are in a very high oxidative state may prevent cancer cells from entering apoptosis ( apoptosis is when a cancer cell commits suicide) When oxidative stress in cancer cells is only slightly above normal, anti-oxidants are then expected to stop their growth and reproduction.
Blood Chemistry: Blood tests are usually taken every 6 to 8 weeks, depending upon the results of each test. Not only is it important to monitor the tumor markers but equally important to keep abreast of the overall health of normal tissues and organs. For example, it is important to learn of the health of the kidneys and liver, whether the body is producing sufficient red and white blood cells, etc. Low albumin levels most often indicate insufficient intake of proteins in the diet and this problem would have to be addressed. CAAT is designed to attack cancer but keep the normal cells and tissues functioning harmoniously.
Whey Protein: This protein food is recommended at the breakfast meal to help meet the daily needs of amino acids for the normal cells of the body, and to help keep albumin levels normal and to help prevent edema. We recommend Whey protein purchased from the Vitamin Shoppe because it is the only brand that we have seen with no phosphorous or additional vitamins added to it.
Grits: Grits are also recommended at the breakfast meal in place of whole grains because it is low in vitamin B-6. Cancer cells require B-6 to manufacture the amino acid Glycine, which is required for DNA synthesis. Grits, instead of whole grains, therefore helps prevent cancer cells from manufacturing DNA and building new blood vessels.
Calcium D-Glucurate: This phytochemical helps the body to retain a compound called Glucuronic acid. This is necessary to eliminate both estrogen and testosterone from the body. This is why Calcium D-Glucurate is added to the regiments of patients with breast & prostate cancers. Calcium D-Glucurate is not to be confused with calcium carbonate, which is nothing more than a calcium supplement.
D-Limonene: This phytochemical found mostly in citrus fruits blocks the process called Isoprenylation, which is necessary for tumor growth factors such as the RAS gene, Epithelial Growth factor, Tyrosine Kinase, and Insulin-Like-Growth-factor, to send their signals into the nucleus of a cancer cell and directs them to grow and divide into more cancer cells.
Tocotrienols: This member of the Vitamin E family also helps shut down Isoprenylation and assists D-Limonene in blocking the actions of the various tumor growth factors. More specifically, tocotrienols shut down an enzyme called HMG-2, which is essential to the synthesis of the building blocks that form the Isoprenylation process.
Niacin: This B-Complex vitamin works with D-limonene and the Tocotrienols to shut down the process of Isoprenylation, which as mentioned above prevents the cancer promoting RAS genes from sending signals into the nucleus of the cell. Niacin also helps deplete thee amino acid Glycine, which cancer cells need to synthesize DNA. And by reducing cholesterole in the body, Niacin helps lower the production of estrogen and testosterone.
Choline: This B-complex vitamin is included in our supplement list to help the liver metabolize Niacin and other compounds and to help fight fatigue that accompanies most forms of cancer.
Selenium: Numerous studies show that this mineral can interfere with the activity of certain genes that promote the growth of cancer and to induce cancer cells to commit suicide (apoptosis)
Perilla Oil: This oil is rich in Alpha Linolenic Acid which can inhibit the growth of cancer cells in several ways. One way is to inhibit the synthesis in the body of a tumor growth promotin hormone called Prostaglandin-2, also, Alpha Linolenic Acid inhibits the actions of certain genes that promote the growth of cancer cells. Linolenic acid is not to be confused with linoleic acid, which is a bad fat that stimulates the growth of cancer cells. This bad fat, linoleic acid, is found in all vegetable oils and nuts (With the exception of coconut oil). Olive oil has the least amount of this bad fat.
Super Miraforte: This herb impairs the synthesis of estrogen from
testosterone in the body and is included in the regiments of women with
breast cancer.
Licorice Root Extract & Pantothenic Acid: This herb and vitamin are
added to the regiment when it is desirable to produce steroid like actions
in the body. Also used to help patient’s gain weight and to inhibit
the growth of lymphomas and leukemia’s.
Resveratrol: This phytochemical blocks the actions of a number of a number of cancer promoting genes thereby causing cancer cells to enter into apoptosis (cell death) and is included in the treatment of all cancers.
Indole-3 Carbinol & D.I.M.: These two phytochemicals block the actions of both estrogen and testosterone and are included in the regiments of both breast and prostate gland cancer.
Melatonin: Numerous studies show that this hormone blocks the synthesis of the cancer promoting chemicals in the body called Leukotrienes, and is included in the treatment of all cancers.
Artho Pro System: This combination of herbs and phytochemicals inhibits the synthesis of the cancer promoting hormone called Prostaglandin-2 and the Leukotriens and replaces the drug celebrex when liver problems are present. The Prostaglandin hormone is over active in most cancers and stimulates cancer growth. The body manufactures the Prostaglandin hormone from the bad fat, Linoleic acid, mentioned above.
Licorice Root Extract & Pantothenic Acid: This HERB and
VITAMIN are added to the regiment when it is desirable to produce
steroid like actions in the body. Used also to help patients gain weight
and ti inhibit the growth of Lymphomas and Leukemias.
CAAT is designed to attack cancer, while keeping normal cells and tissues functioning harmoniously.
* When considering any type of complementary cancer treatment or alternative cancer treatment, always consult with your physician first, as possible interactions could reduce your regimen’s efficacy.
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